PMID- 11035424
OWN - NLM
STAT- MEDLINE
DCOM- 20001120
LR  - 20170214
IS  - 0961-2033 (Print)
IS  - 0961-2033 (Linking)
VI  - 9
IP  - 7
DP  - 2000
TI  - Parvovirus B19 infection associated with the production of anti-neutrophil 
      cytoplasmic antibody (ANCA) and anticardiolipin antibody (aCL).
PG  - 551-4
AB  - We described four patients who had clinical diagnosis of erythema infectiosum and 
      presented with skin rash, polyarthralgia, polyarthritis, and mild fever. 
      Anti-parvovirus B19 IgM and IgG antibodies were found in all four patients and 
      parvovirus B19 DNA was detected in three of the four patients by polymerase chain 
      reaction (PCR) in sera using standard methods. Anticardiolipin antibody (aCL) was 
      positive in three of the four patients included three with anti-beta2 
      glycoprotein I (beta2GPI). The immunoglobulin isotype of aCL was found to be IgM. 
      Anti-neutrophil cytoplasmic antibody (ANCA) included three p-ANCA and one c-ANCA 
      was detected in all four patients by indirect immunofluoresence (IIF). Both 
      anti-proteinase 3 (PR3) and anti-myeloperoxidase (MPO) antibodies were found in 
      two patients whom had polyarthritis for more than 6 months. These data indicate 
      parvovirus B19 may be linked to the induction of an autoimmune response.
FAU - Chou, T N
AU  - Chou TN
AD  - Department of Medicine and Institute of Immunology, Chung Shan Medical and Dental 
      College, Taichung, Taiwan.
FAU - Hsu, T C
AU  - Hsu TC
FAU - Chen, R M
AU  - Chen RM
FAU - Lin, L I
AU  - Lin LI
FAU - Tsay, G J
AU  - Tsay GJ
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Lupus
JT  - Lupus
JID - 9204265
RN  - 0 (Antibodies, Anticardiolipin)
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
RN  - 0 (Autoantibodies)
RN  - 0 (DNA, Viral)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulin M)
SB  - IM
MH  - Adult
MH  - Antibodies, Anticardiolipin/*blood
MH  - Antibodies, Antineutrophil Cytoplasmic/*blood
MH  - Arthritis/blood/complications/*immunology
MH  - Autoantibodies/*blood
MH  - DNA, Viral/blood
MH  - Erythema Infectiosum/complications/*diagnosis/immunology
MH  - Female
MH  - Fluorescent Antibody Technique, Indirect
MH  - Humans
MH  - Immunoglobulin G/blood
MH  - Immunoglobulin M/blood
MH  - Male
MH  - Parvovirus B19, Human/immunology/*isolation & purification
MH  - Polymerase Chain Reaction
EDAT- 2000/10/18 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/10/18 11:00
PHST- 2000/10/18 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/10/18 11:00 [entrez]
AID - 10.1177/096120330000900714 [doi]
PST - ppublish
SO  - Lupus. 2000;9(7):551-4. doi: 10.1177/096120330000900714.