PMID- 11050378
OWN - NLM
STAT- MEDLINE
DCOM- 20001129
LR  - 20190906
IS  - 0736-4679 (Print)
IS  - 0736-4679 (Linking)
VI  - 19
IP  - 3 Suppl
DP  - 2000 Oct
TI  - Low-molecular-weight heparin in patients with non-ST-segment elevation acute 
      coronary syndrome: role in the emergency department.
PG  - 3S-11S
AB  - Intravenous unfractionated heparin (UFH) has been shown to be an effective 
      therapy in reducing the risk of death or myocardial infarction in patients with 
      unstable angina. Low molecular weight heparins demonstrate improved pharmacologic 
      and pharmacokinetic properties relative to standard heparin, and these advantages 
      have been translated into similar or even greater clinical efficacy in several 
      large-scale clinical trials evaluating their use. The simple mode of 
      administration and lack of dependency on anticoagulation monitoring make 
      low-molecular-weight heparins an extremely attractive option in the treatment of 
      patients with acute ischemic coronary syndromes presenting without persistent 
      ST-segment elevation.
FAU - Goodman, S G
AU  - Goodman SG
AD  - University of Toronto and Division of Cardiology, Canadian Heart Research Centre, 
      St. Michael's Hospital, Toronto, Ontario, Canada.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Emerg Med
JT  - The Journal of emergency medicine
JID - 8412174
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
SB  - IM
EIN - J Emerg Med 2001 Jan;20(1):105
MH  - Angina, Unstable/diagnosis/*drug therapy/mortality
MH  - Anticoagulants/*therapeutic use
MH  - Controlled Clinical Trials as Topic
MH  - *Electrocardiography
MH  - *Emergency Service, Hospital
MH  - Female
MH  - Heparin, Low-Molecular-Weight/*therapeutic use
MH  - Humans
MH  - Male
MH  - Myocardial Infarction/diagnosis/*drug therapy/mortality
MH  - Ontario
MH  - Prognosis
MH  - Survival Rate
MH  - Treatment Outcome
RF  - 49
EDAT- 2000/10/26 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/10/26 11:00
PHST- 2000/10/26 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/10/26 11:00 [entrez]
AID - S0736467900002481 [pii]
AID - 10.1016/s0736-4679(00)00248-1 [doi]
PST - ppublish
SO  - J Emerg Med. 2000 Oct;19(3 Suppl):3S-11S. doi: 10.1016/s0736-4679(00)00248-1.