PMID- 11053816
OWN - NLM
STAT- MEDLINE
DCOM- 20010118
LR  - 20190513
IS  - 1010-7940 (Print)
IS  - 1010-7940 (Linking)
VI  - 18
IP  - 5
DP  - 2000 Nov
TI  - Mid-term results of partial left ventriculectomy in end-stage heart disease.
PG  - 550-6
AB  - OBJECTIVE: Immediate and mid-term effectiveness of partial left ventriculectomy 
      (PLV) is assessed in 27 idiopathic dilated cardiomyopathy patients. METHODS: All 
      patients were in New York Heart Association (NYHA) class III (17) or IV (ten). 
      The average left ventricular ejection fraction (LVEF) was 19+/-4% by MUGA, and 
      23+/-4% by digital echocardiography. The mean end-systolic volume (LVESV) was 
      259+/-66 ml and the mean end-diastolic volume (LVEDV) was 342+/-83 ml. Mitral 
      valve replacement was a routine part of the procedure. RESULTS: Operative 
      mortality was 18.5%, a LVEDP>25 mmHg, left atrial diameter>55 mm, pulmonary 
      artery systolic pressure>40 mmHg, congestive hepatomegaly and NYHA class IV being 
      the mortality predictors. Three-year Kaplan-Meier survival was 64+/-10%, 
      including operative mortality; freedom from congestive heart failure was 
      65+/-11%. Functional status improved from 3.2+/-0.4 to 1.5+/-0.6 (P=0.0003). The 
      mean LVEF was dramatically increased after PLV (to 40+/-4%, P=0.0001); LVESV was 
      decreased to 90+/-30 ml (P<0.0001) and LVEDV to 160+/-49ml (P<0.0001). This 
      improvement was sustained during the first 30 months. CONCLUSIONS: PLV is a 
      reasonable approach for end-stage patients, providing sustained dramatic changes 
      in ventricular geometry and functional capacity, especially in the absence of 
      compromised right and diastolic left heart functions. Routine replacement of the 
      mitral valve allows a more liberal ventriculectomy and eliminates mitral 
      regurgitation, and this may help minimize ventricular distention.
FAU - Vural, K M
AU  - Vural KM
AD  - Cardiovascular Surgery Department, Turkiye Yuksek Ihtisas Hospital, Ankara, 
      Turkey. kvural@tr.net
FAU - Tasdemir, O
AU  - Tasdemir O
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur J Cardiothorac Surg
JT  - European journal of cardio-thoracic surgery : official journal of the European 
      Association for Cardio-thoracic Surgery
JID - 8804069
SB  - IM
CIN - Eur J Cardiothorac Surg. 2001 Apr;19(4):537-40. PMID: 11394355
MH  - Activities of Daily Living
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiac Catheterization
MH  - Cardiomyopathy, 
      Dilated/complications/diagnosis/mortality/physiopathology/*surgery
MH  - Exercise Test
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/etiology
MH  - Heart Ventricles/*surgery
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Palliative Care/*methods
MH  - Predictive Value of Tests
MH  - Proportional Hazards Models
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Survival Analysis
MH  - Treatment Outcome
EDAT- 2000/10/29 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/10/29 11:00
PHST- 2000/10/29 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/10/29 11:00 [entrez]
AID - S1010-7940(00)00564-9 [pii]
AID - 10.1016/s1010-7940(00)00564-9 [doi]
PST - ppublish
SO  - Eur J Cardiothorac Surg. 2000 Nov;18(5):550-6. doi: 
      10.1016/s1010-7940(00)00564-9.