PMID- 11055888 OWN - NLM STAT- MEDLINE DCOM- 20010215 LR - 20191104 IS - 0037-1963 (Print) IS - 0037-1963 (Linking) VI - 37 IP - 3 Suppl 5 DP - 2000 Jul TI - Risk assessment of venous thromboembolism in medical patients. PG - 3-6 AB - Medical patients are at risk of venous thromboembolism (VTE). However, the extent of the risk is not well characterized. Risk stratification is an important part of effective thromboprophylactic management. The risks depend on the specific clinical risk factors in individual patients and include age, immobility, and prior history of VTE. Medical patient risk assessment models (RAMs) are not fully developed, but a number of specific risk factors have been characterized. Although at present prophylactic treatment is largely empirical, studies evaluating the effects of higher-dose regimens in at-risk patients are ongoing. Long-term prophylaxis may be of benefit to particular patient populations, including those with congenital and acquired aberrations in hemostasis. Published studies of low-molecular-weight heparins (LMWHs) show that these agents are at least as effective as low-dose unfractionated heparin (UFH), with a trend towards an improved safety profile. The results of ongoing studies will provide further insight into the risk of VTE in this important patient group. FAU - Harenberg, J AU - Harenberg J AD - Department of Internal Medicine, University of Heidelberg, Germany. LA - eng PT - Journal Article PT - Review PL - United States TA - Semin Hematol JT - Seminars in hematology JID - 0404514 RN - 0 (Fibrinolytic Agents) SB - IM MH - Fibrinolytic Agents/adverse effects/therapeutic use MH - Humans MH - Neoplasms/complications MH - Risk Assessment MH - Thromboembolism/*etiology/prevention & control MH - Thrombophilia/complications MH - Venous Thrombosis/*etiology/prevention & control RF - 12 EDAT- 2000/10/31 11:00 MHDA- 2001/03/03 10:01 CRDT- 2000/10/31 11:00 PHST- 2000/10/31 11:00 [pubmed] PHST- 2001/03/03 10:01 [medline] PHST- 2000/10/31 11:00 [entrez] AID - S0037-1963(00)90092-1 [pii] AID - 10.1016/s0037-1963(00)90092-1 [doi] PST - ppublish SO - Semin Hematol. 2000 Jul;37(3 Suppl 5):3-6. doi: 10.1016/s0037-1963(00)90092-1.