PMID- 11055892
OWN - NLM
STAT- MEDLINE
DCOM- 20010215
LR  - 20191104
IS  - 0037-1963 (Print)
IS  - 0037-1963 (Linking)
VI  - 37
IP  - 3 Suppl 5
DP  - 2000 Jul
TI  - Venous thromboembolic disease management of the nonsurgical moderate- and 
      high-risk patient.
PG  - 19-22
AB  - Venous thromboembolism (VTE) is at least as common among medical as in surgical 
      patients, and fatal pulmonary embolism (PE) occurs most commonly in medical 
      patients. As in surgical patients, risk factors and high- and low-risk groups 
      have been identified, but no useful risk assessment models (RAMs) have yet been 
      developed for medical patients. The incidence of VTE varies widely, but a history 
      of previous VTE, age greater than 40 years, obesity, and prolonged immobilization 
      are all associated with an increase In risk. Stroke, spinal cord injury, and 
      cancer patients are at particular risk of VTE. Low-dose unfractionated heparin 
      (UFH), low-molecular-weight heparins (LMWHs), antiplatelet agents, and warfarin 
      reduce the incidence of VTE. Current standards of thromboprophylaxis vary with 
      indication. However, utilization is frequently low, even in high-risk patients. 
      Effective prophylaxis must be tailored to the individual patient, taking into 
      account both the history of the patient and the disease.
FAU - Cohen, A T
AU  - Cohen AT
AD  - Department of Medicine, King's College Hospital, London, UK.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Semin Hematol
JT  - Seminars in hematology
JID - 0404514
RN  - 0 (Anticoagulants)
RN  - 0 (Estrogens)
SB  - IM
MH  - Adult
MH  - Anticoagulants/therapeutic use
MH  - Cardiovascular Diseases/complications
MH  - Estrogens/adverse effects
MH  - Female
MH  - Humans
MH  - Nervous System Diseases/complications
MH  - *Neurosurgical Procedures
MH  - Postoperative Complications/*therapy
MH  - Pregnancy
MH  - Risk Factors
MH  - Thromboembolism/etiology/*prevention & control
MH  - Venous Thrombosis/etiology/*prevention & control
RF  - 16
EDAT- 2000/10/31 11:00
MHDA- 2001/03/03 10:01
CRDT- 2000/10/31 11:00
PHST- 2000/10/31 11:00 [pubmed]
PHST- 2001/03/03 10:01 [medline]
PHST- 2000/10/31 11:00 [entrez]
AID - S0037-1963(00)90096-9 [pii]
AID - 10.1016/s0037-1963(00)90096-9 [doi]
PST - ppublish
SO  - Semin Hematol. 2000 Jul;37(3 Suppl 5):19-22. doi: 10.1016/s0037-1963(00)90096-9.