PMID- 11059524 OWN - NLM STAT- MEDLINE DCOM- 20001120 LR - 20190921 IS - 0277-0903 (Print) IS - 0277-0903 (Linking) VI - 37 IP - 7 DP - 2000 TI - Breastfeeding and asthma among Brazilian children. PG - 575-83 AB - We examined the association of breastfeeding and the presence of chronic respiratory symptoms among 5,182 Brazilian schoolchildren 7-14 years of age who were participants in the International Study on Asthma and Allergies in Childhood (ISAAC). The prevalence of medically diagnosed asthma and current wheeze were respectively 4.6% (95% confidence interval [CI] 4.0%-5.2%) and 11.9% (95% CI 11.0%-12.8%). Ninety percent of the mothers in our study population had breastfed their child. After adjusting for potential confounding factors, we found that children who had not been breastfed were more likely to have a medical diagnosis of asthma (odds ration [OR] = 1 .51, 95% CI 1.00-2.51), experience current wheeze (OR = 1.29, 95% CI 0.96-1.74), and wheeze after exercise (OR = 1.51, 95% CI 1.01-2.27) than children who had been breastfed for more than 6 months. This effect was only present among children with no family history of asthma (OR = 1.54, 95% CI 0.90-2.42 for medical diagnosis of asthma; OR = 1.27, 95% CI 0.93-1.75 for current wheezing; and OR = 1.74, 95% CI 1.12-2.6 for wheeze after exercise). We conclude that the low prevalence of asthma and wheeze observed in our population may be partly related to the high level of breastfeeding. FAU - Romieu, I AU - Romieu I AD - Pan American Health Organization, Mexico. iromieu@insp3.insp.mx FAU - Werneck, G AU - Werneck G FAU - Ruiz Velasco, S AU - Ruiz Velasco S FAU - White, M AU - White M FAU - Hernandez, M AU - Hernandez M LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - England TA - J Asthma JT - The Journal of asthma : official journal of the Association for the Care of Asthma JID - 8106454 SB - IM MH - Adolescent MH - Asthma/*epidemiology/etiology MH - Brazil/epidemiology MH - *Breast Feeding MH - Child MH - Female MH - Humans MH - Male MH - Prevalence MH - Respiratory Sounds MH - Risk Assessment EDAT- 2000/11/04 11:00 MHDA- 2001/02/28 10:01 CRDT- 2000/11/04 11:00 PHST- 2000/11/04 11:00 [pubmed] PHST- 2001/02/28 10:01 [medline] PHST- 2000/11/04 11:00 [entrez] AID - 10.3109/02770900009090812 [doi] PST - ppublish SO - J Asthma. 2000;37(7):575-83. doi: 10.3109/02770900009090812.