PMID- 11063801
OWN - NLM
STAT- MEDLINE
DCOM- 20001204
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 121
IP  - 2
DP  - 2000 Sep
TI  - Cytogenetic and fluorescence in situ hybridization studies in four cases of 
      plasma cell leukemia.
PG  - 163-6
AB  - We present a cytogenetic and fluorescence in situ hybridization (FISH) study, 
      using centromeric probes for chromosomes 3, 7, 11, and 18, TP53 gene (17p13), and 
      RB-1 locus (13q14) DNA probes, in four cases of plasma cell leukemia (PCL). Among 
      the four cases, three presented monosomy of the RB-1 locus and one monoallelic 
      deletion of the TP53 gene. The present report shows the usefulness of the FISH 
      technique to detect abnormalities not previously observed by conventional 
      cytogenetics.
FAU - Lloveras, E
AU  - Lloveras E
AD  - Laboratori de Citologia Hematologica/Laboratori de Referencia de Catalunya, 
      Unitat d'Hematologia, Hospital del Mar, Barcelona, Spain.
FAU - Sole, F
AU  - Sole F
FAU - Espinet, B
AU  - Espinet B
FAU - Besses, C
AU  - Besses C
FAU - Asensio, A
AU  - Asensio A
FAU - Abella, E
AU  - Abella E
FAU - Woessner, S
AU  - Woessner S
FAU - Florensa, L
AU  - Florensa L
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (DNA Probes)
RN  - 0 (DNA, Satellite)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - DNA Probes
MH  - DNA, Satellite
MH  - Female
MH  - Genes, Retinoblastoma
MH  - Genes, p53
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Leukemia, Plasma Cell/*genetics
MH  - Male
EDAT- 2000/11/07 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/11/07 11:00
PHST- 2000/11/07 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/11/07 11:00 [entrez]
AID - S0165-4608(00)00243-0 [pii]
AID - 10.1016/s0165-4608(00)00243-0 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 2000 Sep;121(2):163-6. doi: 
      10.1016/s0165-4608(00)00243-0.