PMID- 11064440 OWN - NLM STAT- MEDLINE DCOM- 20010104 LR - 20170214 IS - 1352-4585 (Print) IS - 1352-4585 (Linking) VI - 6 IP - 5 DP - 2000 Oct TI - Histocompatibility antigen (HLA) associations with multiple sclerosis in Iran. PG - 317-9 AB - Human leukocyte antigen (HLA) types were obtained from 79 Iranian patients with multiple sclerosis and compared with 100 controls. The prevalence of HLA-A24 (30.3% versus 18.0%), HLA-DR2 (43.0% versus 28. 0%) and HLA-DR15 (36.7% versus 23.0%) were significantly increased in multiple sclerosis patients compared with controls. However age at onset, and disease status (relapsing - remitting or primary progressive) did not show an association with any particular HLA type. Multiple Sclerosis (2000) 6 317 - 319 FAU - Kalanie, H AU - Kalanie H AD - Department of Neurology, Shohada Hospital, Tajrish, Tehran, Iran. FAU - Kamgooyan, M AU - Kamgooyan M FAU - Sadeghian, H AU - Sadeghian H FAU - Kalanie, A R AU - Kalanie AR LA - eng PT - Journal Article PL - England TA - Mult Scler JT - Multiple sclerosis (Houndmills, Basingstoke, England) JID - 9509185 RN - 0 (HLA-A Antigens) RN - 0 (HLA-A24 Antigen) RN - 0 (HLA-DR Antigens) RN - 0 (HLA-DR Serological Subtypes) RN - 0 (HLA-DR15 antigen) RN - 0 (HLA-DR2 Antigen) SB - IM MH - Adolescent MH - Adult MH - Age of Onset MH - B-Lymphocytes/immunology MH - Female MH - Genetic Predisposition to Disease MH - HLA-A Antigens/*analysis/*immunology MH - HLA-A24 Antigen MH - HLA-DR Antigens/*analysis/*immunology MH - HLA-DR Serological Subtypes MH - HLA-DR2 Antigen/analysis/immunology MH - Humans MH - Iran/epidemiology MH - Male MH - Middle Aged MH - Multiple Sclerosis, Relapsing-Remitting/epidemiology/genetics/*immunology EDAT- 2000/11/07 11:00 MHDA- 2001/02/28 10:01 CRDT- 2000/11/07 11:00 PHST- 2000/11/07 11:00 [pubmed] PHST- 2001/02/28 10:01 [medline] PHST- 2000/11/07 11:00 [entrez] AID - 10.1177/135245850000600504 [doi] PST - ppublish SO - Mult Scler. 2000 Oct;6(5):317-9. doi: 10.1177/135245850000600504.