PMID- 11086553 OWN - NLM STAT- MEDLINE DCOM- 20001221 LR - 20170214 IS - 0706-7437 (Print) IS - 0706-7437 (Linking) VI - 45 IP - 8 DP - 2000 Oct TI - First-episode psychosis: a comparative review of diagnostic evolution and predictive variables in adolescents versus adults. PG - 710-6 AB - OBJECTIVE: To review the diagnostic evolution and predictive variables of diagnosis and outcome in first-episode psychosis in adolescents (age 13-19 years) and adults. METHOD: Literature was reviewed through MEDLINE, Psycinfo, and PubMed, and supplemented by selected bibliographies. RESULTS: First-episode psychosis in the adolescent population has greater diagnostic instability than in adults. We identified trends in the predictive variables of diagnosis and outcome: 1) Premorbid adjustment (that is, personality) in adolescents and Global Assessment of Functioning (GAF) both before and after first-episode psychosis in adolescents and adults are the best predictors of diagnosis; 2) GAF (before and after) is the best predictor of outcome in both adolescents and adults. CONCLUSION: Adolescent-onset psychosis appears to be in continuity with adult-onset psychosis. The greater diagnostic instability in adolescents and the absence of significant data on predictive variables suggest a need for specialized and continuous care and research in the adolescent population. FAU - Menezes, N M AU - Menezes NM AD - Department of Psychiatry, McGill University, Montreal, Quebec. nmenez@po-mcgill.ca FAU - Milovan, E AU - Milovan E LA - eng PT - Comparative Study PT - Journal Article PT - Review PL - United States TA - Can J Psychiatry JT - Canadian journal of psychiatry. Revue canadienne de psychiatrie JID - 7904187 SB - IM MH - Adolescent MH - Adult MH - Child, Preschool MH - Disease Progression MH - Humans MH - Predictive Value of Tests MH - Psychology, Adolescent MH - Psychotic Disorders/*diagnosis/*psychology/therapy MH - Recurrence MH - Severity of Illness Index RF - 49 EDAT- 2000/11/22 11:00 MHDA- 2001/02/28 10:01 CRDT- 2000/11/22 11:00 PHST- 2000/11/22 11:00 [pubmed] PHST- 2001/02/28 10:01 [medline] PHST- 2000/11/22 11:00 [entrez] AID - 10.1177/070674370004500803 [doi] PST - ppublish SO - Can J Psychiatry. 2000 Oct;45(8):710-6. doi: 10.1177/070674370004500803.