PMID- 11094431 OWN - NLM STAT- MEDLINE DCOM- 20010315 LR - 20181113 IS - 1465-9905 (Print) IS - 1465-9913 (Electronic) IS - 1465-9905 (Linking) VI - 2 IP - 3 DP - 2000 TI - Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. PG - 208-11 AB - Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these major histocompatibility complex (MHC) class II molecules have been developed to generate humanized models for RA. The relevance of these models for understanding RA will be discussed. FAU - Fugger, L AU - Fugger L AD - Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Denmark. fugger@inet.uni2.dk FAU - Svejgaard, A AU - Svejgaard A LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20000425 PL - England TA - Arthritis Res JT - Arthritis research JID - 100913255 RN - 0 (HLA-DR4 Antigen) SB - IM CIN - Arthritis Res. 2000;2(3):203-4. PMID: 11094429 MH - Animals MH - Arthritis, Rheumatoid/*immunology MH - Disease Models, Animal MH - HLA-DR4 Antigen/genetics/*immunology MH - Humans MH - Mice MH - Mice, Transgenic PMC - PMC130004 EDAT- 2000/11/30 11:00 MHDA- 2001/03/17 10:01 PMCR- 2000/04/25 CRDT- 2000/11/30 11:00 PHST- 2000/02/09 00:00 [received] PHST- 2000/02/29 00:00 [accepted] PHST- 2000/11/30 11:00 [pubmed] PHST- 2001/03/17 10:01 [medline] PHST- 2000/11/30 11:00 [entrez] PHST- 2000/04/25 00:00 [pmc-release] AID - ar89 [pii] AID - 10.1186/ar89 [doi] PST - ppublish SO - Arthritis Res. 2000;2(3):208-11. doi: 10.1186/ar89. Epub 2000 Apr 25.