PMID- 11103724
OWN - NLM
STAT- MEDLINE
DCOM- 20001214
LR  - 20131121
IS  - 0735-6757 (Print)
IS  - 0735-6757 (Linking)
VI  - 18
IP  - 7
DP  - 2000 Nov
TI  - Etomidate versus succinylcholine for intubation in an air medical setting.
PG  - 757-63
AB  - The objective was to compare rates of successful endotracheal intubation (ETI) 
      and requirement for multiple ETI attempts in patients receiving etomidate (ETOM) 
      versus succinylcholine (SUX). This retrospective study analyzed adults in whom 
      oral ETI was attempted by a helicopter EMS (HEMS) service between July 1997 to 
      July 1999. Data were from records of the HEMS service, which uses a RN/EMTP crew; 
      analysis was with chi-square and logistic regression (P = .05). ETI was 
      successful in 269 (97.8%) of 275 patients, with multiple attempts occurring in 54 
      (20.1%) of 269. Success rates for SUX (209 of 213, 98.1%) and ETOM (60 of 62, 
      96.8%) were similar (P = .62). However, of 60 ETOM patients successfully 
      intubated, 7 (11.7%) required rescue succinylcholine. When these patients are 
      tallied as ETOM failures and SUX successes, resultant success rates for ETOM 
      (86.9%) and SUX (98.2%) are different (P = .001). ETOM patients were more likely 
      (P = .004) than SUX patients to require multiple attempts (33.3% versus 16.3%). 
      ETI success rates were high in patients receiving SUX or ETOM as primary adjuncts 
      for airway control, but initial success was more likely with SUX, and ETOM 
      patients were more likely to require multiple attempts.
FAU - Kociszewski, C
AU  - Kociszewski C
AD  - Boston Medflight Critical Care Transport Service, MA, USA.
FAU - Thomas, S H
AU  - Thomas SH
FAU - Harrison, T
AU  - Harrison T
FAU - Wedel, S K
AU  - Wedel SK
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Am J Emerg Med
JT  - The American journal of emergency medicine
JID - 8309942
RN  - 0 (Hypnotics and Sedatives)
RN  - 0 (Neuromuscular Depolarizing Agents)
RN  - J2R869A8YF (Succinylcholine)
RN  - Z22628B598 (Etomidate)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Air Ambulances
MH  - Etomidate/*pharmacology/therapeutic use
MH  - Female
MH  - Humans
MH  - Hypnotics and Sedatives/*pharmacology/therapeutic use
MH  - Intubation, Intratracheal/*methods
MH  - Male
MH  - Middle Aged
MH  - Neuromuscular Depolarizing Agents/*pharmacology/therapeutic use
MH  - Retrospective Studies
MH  - Succinylcholine/*pharmacology/therapeutic use
EDAT- 2000/12/05 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/12/05 11:00
PHST- 2000/12/05 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/12/05 11:00 [entrez]
AID - S0735-6757(00)33803-7 [pii]
AID - 10.1053/ajem.2000.18033 [doi]
PST - ppublish
SO  - Am J Emerg Med. 2000 Nov;18(7):757-63. doi: 10.1053/ajem.2000.18033.