PMID- 11106826 OWN - NLM STAT- MEDLINE DCOM- 20001222 LR - 20190816 IS - 0165-4608 (Print) IS - 0165-4608 (Linking) VI - 122 IP - 2 DP - 2000 Oct 15 TI - CALM-AF10 fusion gene in leukemias: simple and inversion-associated translocation (10;11). PG - 137-40 AB - A translocation (10;11)(p12;q14) was observed in two children, one with acute eosinophilic leukemia and the other with acute T-cell lymphoblastic leukemia. The presence of CALM-AF10 fusion was ascertained by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis. Fluorescence in situ hybridization (FISH) analysis showed that AF10 gene splitting was associated with partial inversion of chromosome 11 in the first patient. In addition, FISH analysis also determined the orientation of the CALM gene, 5' telomere to 3' centromere on 11q. FAU - Salmon-Nguyen, F AU - Salmon-Nguyen F AD - Unite INSERM U 434 and SD 401 No434 CNRS, Institut de Genetique Moleculaire, 27 rue Juliette dodu, 75010, Paris, France. FAU - Busson, M AU - Busson M FAU - Daniel, M AU - Daniel M FAU - Leblanc, T AU - Leblanc T FAU - Bernard, O A AU - Bernard OA FAU - Berger, R AU - Berger R LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Cancer Genet Cytogenet JT - Cancer genetics and cytogenetics JID - 7909240 RN - 0 (AF10-CALM fusion protein, human) RN - 0 (DNA, Complementary) RN - 0 (Oncogene Proteins, Fusion) SB - IM MH - Adolescent MH - Child MH - Chromosome Inversion MH - Chromosomes, Human, Pair 10/genetics MH - Chromosomes, Human, Pair 11/genetics MH - DNA, Complementary/chemistry/genetics MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - Leukemia, Eosinophilic, Acute/*genetics/pathology MH - Leukemia-Lymphoma, Adult T-Cell/*genetics/pathology MH - Oncogene Proteins, Fusion/*genetics MH - Reverse Transcriptase Polymerase Chain Reaction MH - Sequence Analysis, DNA MH - Translocation, Genetic EDAT- 2000/12/07 11:00 MHDA- 2001/02/28 10:01 CRDT- 2000/12/07 11:00 PHST- 2000/12/07 11:00 [pubmed] PHST- 2001/02/28 10:01 [medline] PHST- 2000/12/07 11:00 [entrez] AID - S0165460800002776 [pii] AID - 10.1016/s0165-4608(00)00277-6 [doi] PST - ppublish SO - Cancer Genet Cytogenet. 2000 Oct 15;122(2):137-40. doi: 10.1016/s0165-4608(00)00277-6.