PMID- 11118917
OWN - NLM
STAT- MEDLINE
DCOM- 20010531
LR  - 20191104
IS  - 0929-8266 (Print)
IS  - 0929-8266 (Linking)
VI  - 12
IP  - 2
DP  - 2000 Dec
TI  - Correlations among prostatic biopsy results, transrectal ultrasound findings and 
      PSA levels in diagnosing prostate adenocarcinoma.
PG  - 103-13
AB  - OBJECTIVE: The objective of this study was to evaluate transrectal ultrasound 
      (TRUS) findings and prostate-specific antigen (PSA) levels in relation to 
      prostatic biopsy results and to analyze their individual and combined 
      performances in diagnosing prostate adenocarcinoma (PAC). METHODS: Men (n=143) 
      with PSA levels above 4 ng/ml underwent TRUS and randomized ultrasound-guided 
      prostatic biopsy through the peripheral zone, including additional hypoechoic 
      nodules biopsies, if they were noted on TRUS. Data related to TRUS, biopsy, and 
      PSA level results were then correlated. RESULTS: A significant correlation 
      between TRUS images suspicious for PAC and a biopsy-confirmed diagnosis of PAC, 
      or between the lack of such images and a negative biopsy result, was not found. 
      However, a significant correlation was found between positive biopsy results and 
      PSA levels greater or equal to 10 ng/ml. The sensitivity of transrectal 
      ultrasound in making a diagnosis of PAC was 63%, whereas its specificity was 73%. 
      CONCLUSION: We conclude that while the separate performances of these 
      examinations were not effective in diagnosing PAC, the integrated use of these 
      methods was more adequate for making the diagnosis.
FAU - Kokeny, G P
AU  - Kokeny GP
AD  - Department of Radiology, School of Medicine, University of Sao Paulo, Sao Paulo, 
      Brazil.
FAU - Cerri, G G
AU  - Cerri GG
FAU - de Oliveira Cerri, L M
AU  - de Oliveira Cerri LM
FAU - de Barros, N
AU  - de Barros N
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Ireland
TA  - Eur J Ultrasound
JT  - European journal of ultrasound : official journal of the European Federation of 
      Societies for Ultrasound in Medicine and Biology
JID - 9440414
RN  - EC 3.4.21.77 (Prostate-Specific Antigen)
SB  - IM
MH  - Adenocarcinoma/blood/diagnostic imaging/*pathology
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biopsy
MH  - Chi-Square Distribution
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prostate-Specific Antigen/blood
MH  - Prostatic Neoplasms/blood/diagnostic imaging/*pathology
MH  - Ultrasonography
EDAT- 2000/12/19 11:00
MHDA- 2001/06/02 10:01
CRDT- 2000/12/19 11:00
PHST- 2000/12/19 11:00 [pubmed]
PHST- 2001/06/02 10:01 [medline]
PHST- 2000/12/19 11:00 [entrez]
AID - S0929-8266(00)00100-2 [pii]
AID - 10.1016/s0929-8266(00)00100-2 [doi]
PST - ppublish
SO  - Eur J Ultrasound. 2000 Dec;12(2):103-13. doi: 10.1016/s0929-8266(00)00100-2.