PMID- 11179271
OWN - NLM
STAT- MEDLINE
DCOM- 20010524
LR  - 20191210
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Print)
IS  - 1355-6037 (Linking)
VI  - 85
IP  - 3
DP  - 2001 Mar
TI  - Do patients over 40 years of age benefit from surgical closure of atrial septal 
      defects?
PG  - 300-3
AB  - OBJECTIVE: To determine the value of surgical closure of atrial septal defects in 
      patients over 40 years of age. METHODS: Retrospective analysis of 76 patients (63 
      women, 13 men), age range 40-62 years (mean (SD) 45.8 (5.1) years), who underwent 
      surgical repair of atrial septal defect. Pre- and postoperative clinical status 
      (New York Heart Association (NYHA) functional class) was assessed, and ECG, x 
      ray, and echocardiographic investigations performed. Follow up was between 1 and 
      17 years. RESULTS: One operative and one late death occurred during the study 
      period. Before operation, 47 patients (61.8%) were in NYHA functional classes III 
      and IV. After operation, 61 patients (82.4%) were in classes I and II. Four 
      patients had atrial fibrillation before surgery versus nine after surgery. Before 
      operation, 52 patients had intensified pulmonary vascularity compared with only 
      seven after operation. Echocardiographic examination showed a significant 
      reduction in right ventricular dimension (4.10 (0.91) v 2.95 (0.36) cm, p < 
      0.001). No residual intracardiac shunts were identified on echocardiographic 
      follow up. CONCLUSIONS: Surgical closure of atrial septal defects in patients 
      over 40 years old can improve their clinical status and prevent right ventricular 
      dilatation and insufficiency.
FAU - Jemielity, M
AU  - Jemielity M
AD  - Department of Cardiac Surgery, Institute of Cardiology, Karol Marcinkowski 
      University of Medical Sciences, Poznan, Poland. mjemielity@poland.com
FAU - Dyszkiewicz, W
AU  - Dyszkiewicz W
FAU - Paluszkiewicz, L
AU  - Paluszkiewicz L
FAU - Perek, B
AU  - Perek B
FAU - Buczkowski, P
AU  - Buczkowski P
FAU - Ponizynski, A
AU  - Ponizynski A
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
SB  - IM
CIN - Heart. 2001 Mar;85(3):249-50. PMID: 11179255
MH  - Adult
MH  - Age Factors
MH  - Arrhythmias, Cardiac/etiology
MH  - Female
MH  - Heart Septal Defects, Atrial/complications/mortality/physiopathology/*surgery
MH  - Heart Ventricles/anatomy & histology/diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Satisfaction
MH  - Retrospective Studies
MH  - Ultrasonography
PMC - PMC1729662
EDAT- 2001/02/17 11:00
MHDA- 2001/05/26 10:01
PMCR- 2004/03/01
CRDT- 2001/02/17 11:00
PHST- 2001/02/17 11:00 [pubmed]
PHST- 2001/05/26 10:01 [medline]
PHST- 2001/02/17 11:00 [entrez]
PHST- 2004/03/01 00:00 [pmc-release]
AID - 10.1136/heart.85.3.300 [doi]
PST - ppublish
SO  - Heart. 2001 Mar;85(3):300-3. doi: 10.1136/heart.85.3.300.