PMID- 11195898
OWN - NLM
STAT- MEDLINE
DCOM- 20010503
LR  - 20190906
IS  - 0036-5599 (Print)
IS  - 0036-5599 (Linking)
VI  - 34
IP  - 6
DP  - 2000 Dec
TI  - Evaluation of human leukocyte antigen expression in patients with prostate 
      cancer.
PG  - 352-4
AB  - OBJECTIVE: The aim of this prospective study was to evaluate the possible 
      relationship between human major histocompatibility antigens [human leukocyte 
      antigen (HLA)] and prostatic adenocarcinoma. MATERIAL AND METHODS: This clinical 
      study was performed in 30 patients with histologically proven prostatic 
      adenocarcinoma and 102 healthy men. HLA A, B and DR groups were evaluated in all 
      patients. RESULTS: Of the HLAs examined, A2, A10, A28, A14, DR6, DR7 and DR9 were 
      found to be accumulated significantly in patients with prostatic cancer in 
      comparison with the healthy subjects. Apart from HLA A2 and DR7, the relative 
      risk has been found to be over 2 in patients demonstrating these antigens. 
      CONCLUSIONS: Although there was a statistically significant difference with 
      respect to HLA accumulation between patients with prostate cancer and healthy 
      subjects, larger series of patients including other parameters are needed.
FAU - Yagci, F
AU  - Yagci F
AD  - Department of Urology, Sahinbey Hospital, University of Gaziantep, Medical 
      School, Turkey.
FAU - Sarica, K
AU  - Sarica K
LA  - eng
PT  - Journal Article
PL  - England
TA  - Scand J Urol Nephrol
JT  - Scandinavian journal of urology and nephrology
JID - 0114501
RN  - 0 (Antigens, Neoplasm)
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adenocarcinoma/*genetics/*immunology
MH  - Antigens, Neoplasm/*biosynthesis/genetics
MH  - *Gene Expression Regulation, Neoplastic
MH  - HLA Antigens/*biosynthesis/genetics
MH  - Humans
MH  - Male
MH  - Prospective Studies
MH  - Prostatic Neoplasms/*genetics/*immunology
EDAT- 2001/02/24 12:00
MHDA- 2001/05/05 10:01
CRDT- 2001/02/24 12:00
PHST- 2001/02/24 12:00 [pubmed]
PHST- 2001/05/05 10:01 [medline]
PHST- 2001/02/24 12:00 [entrez]
AID - 10.1080/003655900455413 [doi]
PST - ppublish
SO  - Scand J Urol Nephrol. 2000 Dec;34(6):352-4. doi: 10.1080/003655900455413.