PMID- 11205128
OWN - NLM
STAT- MEDLINE
DCOM- 20010222
LR  - 20190815
IS  - 0304-8608 (Print)
IS  - 0304-8608 (Linking)
VI  - 145
IP  - 11
DP  - 2000
TI  - Experimental infection of colostrum deprived piglets with porcine circovirus 2 
      (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) 
      potentiates PCV2 replication.
PG  - 2421-9
AB  - Experimental infection of colostrum-deprived (CD) pigs with a combined inoculum 
      of porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome 
      virus (PRRSV) potentiated the replication and distribution of PCV2 virus, when 
      compared with pigs inoculated with PCV2 alone. The replication and distribution 
      of PRRSV in dually infected pigs was not enhanced, when compared to pigs 
      inoculated with PRRSV alone. The mechanisms involved in the potentiation of PCV2 
      replication in PCV2/PRRSV and PCV2/porcine parvovirus (PPV) dually infected pigs 
      may relate to the fact that monocyte/macrophage cell types are common targets of 
      these 3 viruses.
FAU - Allan, G M
AU  - Allan GM
AD  - Virology Department, Department of Agriculture and Rural Development for N. 
      Ireland, Belfast.
FAU - McNeilly, F
AU  - McNeilly F
FAU - Ellis, J
AU  - Ellis J
FAU - Krakowka, S
AU  - Krakowka S
FAU - Meehan, B
AU  - Meehan B
FAU - McNair, I
AU  - McNair I
FAU - Walker, I
AU  - Walker I
FAU - Kennedy, S
AU  - Kennedy S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Austria
TA  - Arch Virol
JT  - Archives of virology
JID - 7506870
RN  - 0 (Antibodies, Viral)
RN  - 0 (Antigens, Viral)
SB  - IM
MH  - Animals
MH  - Animals, Newborn
MH  - Antibodies, Viral/blood
MH  - Antigens, Viral/analysis
MH  - Circoviridae Infections/complications/*veterinary/virology
MH  - Circovirus/immunology/isolation & purification/*physiology
MH  - Colostrum/immunology
MH  - Fluorescent Antibody Technique
MH  - Porcine Reproductive and Respiratory Syndrome/*virology
MH  - Porcine respiratory and reproductive syndrome virus/immunology/isolation & 
      purification/*physiology
MH  - Random Allocation
MH  - Swine
MH  - Swine Diseases/*virology
MH  - *Virus Replication
EDAT- 2001/02/24 12:00
MHDA- 2001/03/03 10:01
CRDT- 2001/02/24 12:00
PHST- 2001/02/24 12:00 [pubmed]
PHST- 2001/03/03 10:01 [medline]
PHST- 2001/02/24 12:00 [entrez]
AID - 10.1007/s007050070031 [doi]
PST - ppublish
SO  - Arch Virol. 2000;145(11):2421-9. doi: 10.1007/s007050070031.