PMID- 11215916
OWN - NLM
STAT- MEDLINE
DCOM- 20010621
LR  - 20190513
IS  - 0891-6640 (Print)
IS  - 0891-6640 (Linking)
VI  - 15
IP  - 1
DP  - 2001 Jan-Feb
TI  - Food sensitivity in cats with chronic idiopathic gastrointestinal problems.
PG  - 7-13
AB  - The objectives of this study were to investigate the prevalence of food 
      sensitivity in cats with chronic idiopathic gastrointestinal problems, to 
      identify the food ingredients responsible, and to characterize the clinical 
      features. Seventy cats that presented for chronic gastrointestinal signs 
      underwent diagnostic investigation. Fifty-five cats had idiopathic problems and 
      were entered into the study. Diagnosis of food sensitivity was made by dietary 
      elimination-challenge studies by using commercial selected-protein diets as the 
      elimination diet. Sixteen (29%) of the 55 cats with chronic idiopathic 
      gastrointestinal problems were diagnosed as food sensitive. The clinical signs of 
      another 11 cats (20%) resolved on the elimination diet but did not recur after 
      challenge with their previous diet. The foods or food ingredients responsible for 
      the clinical signs were dietary staples. Fifty percent of affected cats were 
      sensitive to more than 1 food ingredient. The clinical feature most suggestive of 
      food sensitivity was concurrent occurrence of gastrointestinal and dermatological 
      signs. Weight loss occurred in 11 of the affected cats, and large-bowel diarrhea 
      was more common than small-bowel diarrhea. Assay of serum antigen-specific 
      immunoglobulin E (IgE) had limited value as a screening test, and gastroscopic 
      food sensitivity testing was not helpful. In conclusion, adverse reactions to 
      dietary staples were common in this population of cats, and they responded well 
      to selected-protein diets. Diagnosis requires dietary elimination-challenge 
      trials and cannot be made on the basis of clinical signs, routine 
      clinicopathological data, serum antigen-specific IgE assay, gastroscopic food 
      sensitivity testing, or gastrointestinal biopsy.
FAU - Guilford, W G
AU  - Guilford WG
AD  - Institute of Veterinary, Animal, and Biomedical Sciences, Massey University, 
      Palmerston North, New Zealand. W.G.Guilford@massey.ac.nz
FAU - Jones, B R
AU  - Jones BR
FAU - Markwell, P J
AU  - Markwell PJ
FAU - Arthur, D G
AU  - Arthur DG
FAU - Collett, M G
AU  - Collett MG
FAU - Harte, J G
AU  - Harte JG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Vet Intern Med
JT  - Journal of veterinary internal medicine
JID - 8708660
RN  - 0 (Dietary Proteins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
CIN - J Vet Intern Med. 2001 Jan-Feb;15(1):5-6. PMID: 11215912
MH  - Animal Feed/*adverse effects
MH  - Animals
MH  - Cat Diseases/*diagnosis/*epidemiology/therapy
MH  - Cats
MH  - Diarrhea/veterinary
MH  - Dietary Proteins/*administration & dosage
MH  - Female
MH  - Food Hypersensitivity/diagnosis/epidemiology/therapy/*veterinary
MH  - Gastrointestinal Diseases/diagnosis/epidemiology/therapy/*veterinary
MH  - Immunoglobulin E/analysis
MH  - Male
MH  - Prevalence
MH  - Vomiting/veterinary
MH  - Weight Loss
EDAT- 2001/02/24 12:00
MHDA- 2001/06/22 10:01
CRDT- 2001/02/24 12:00
PHST- 2001/02/24 12:00 [pubmed]
PHST- 2001/06/22 10:01 [medline]
PHST- 2001/02/24 12:00 [entrez]
AID - 10.1892/0891-6640(2001)015<0007:fsicwc>2.3.co;2 [doi]
PST - ppublish
SO  - J Vet Intern Med. 2001 Jan-Feb;15(1):7-13. doi: 
      10.1892/0891-6640(2001)015<0007:fsicwc>2.3.co;2.