PMID- 11225749
OWN - NLM
STAT- MEDLINE
DCOM- 20010322
LR  - 20221207
IS  - 1462-8902 (Print)
IS  - 1462-8902 (Linking)
VI  - 2
IP  - 5
DP  - 2000 Oct
TI  - Variations in plasma soluble tumour necrosis factor receptors after diet-induced 
      weight loss in obesity.
PG  - 323-5
AB  - The aim of this study was to investigate the variations in the plasma levels of 
      the soluble tumour necrosis factor receptor type-I (sTNFR-I) and type-II 
      (sTNFR-II) during weight loss which was induced by 3 weeks on a very low calorie 
      diet (3.9+/-0.1 MJ/day), in 17 non-diabetic obese women. Plasma sTNFR-I 
      concentrations decreased significantly after weight loss (p < 0.05), but there 
      was no significant change in plasma sTNFR-II. As the diet was associated with a 
      significant decrease in body fat mass (=2.5 kg), this result supports the 
      emerging concept that adipose tissue can produce significant amounts of sTNFR-I 
      and that this production can be modified by weight loss in human obesity.
FAU - Bastard, J P
AU  - Bastard JP
AD  - Service de Biochimie, H pital de la Salpetriere, Paris, France. 
      jean-philippe.bastard@tnn.ap-hop-paris.fr
FAU - Jardel, C
AU  - Jardel C
FAU - Bruckert, E
AU  - Bruckert E
FAU - Vidal, H
AU  - Vidal H
FAU - Hainque, B
AU  - Hainque B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Diabetes Obes Metab
JT  - Diabetes, obesity & metabolism
JID - 100883645
RN  - 0 (Antigens, CD)
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
RN  - 0 (Receptors, Tumor Necrosis Factor)
RN  - 0 (Receptors, Tumor Necrosis Factor, Type I)
RN  - 0 (Receptors, Tumor Necrosis Factor, Type II)
SB  - IM
MH  - Antigens, CD/*blood
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - *Diet, Reducing
MH  - Energy Intake
MH  - Female
MH  - Humans
MH  - Insulin/blood
MH  - Insulin Resistance
MH  - Middle Aged
MH  - Obesity/*blood/physiopathology
MH  - Receptors, Tumor Necrosis Factor/*blood
MH  - Receptors, Tumor Necrosis Factor, Type I
MH  - Receptors, Tumor Necrosis Factor, Type II
MH  - Weight Loss/*physiology
MH  - White People
EDAT- 2001/02/28 10:00
MHDA- 2001/03/27 10:01
CRDT- 2001/02/28 10:00
PHST- 2001/02/28 10:00 [pubmed]
PHST- 2001/03/27 10:01 [medline]
PHST- 2001/02/28 10:00 [entrez]
AID - 10.1046/j.1463-1326.2000.00090.x [doi]
PST - ppublish
SO  - Diabetes Obes Metab. 2000 Oct;2(5):323-5. doi: 10.1046/j.1463-1326.2000.00090.x.