PMID- 11246362
OWN - NLM
STAT- MEDLINE
DCOM- 20010830
LR  - 20190817
IS  - 0192-0790 (Print)
IS  - 0192-0790 (Linking)
VI  - 32
IP  - 3
DP  - 2001 Mar
TI  - The "serendipitous" surgical cure of the Zollinger-Ellison syndrome in a patient 
      with multiple endocrine neoplasia type 1 despite an unsuspected diagnosis of 
      either disease.
PG  - 268-71
AB  - Zollinger-Ellison syndrome (ZES) is a relatively uncommon disease that usually 
      presents with peptic ulcer disease or refractory diarrhea. It occurs as a 
      component of multiple endocrine neoplasia type 1 (MEN-1) syndrome in more than 
      25% of cases. Surgical management of MEN-1 ZES remains controversial. In this 
      case report, we describe the serendipitous cure of ZES in a patient with 
      recurrent peptic ulcer disease who underwent two surgical procedures. The 
      diagnosis of MEN-1 ZES syndrome was neither suspected nor recognized during 
      either operation. This case is presented to highlight the important principles in 
      the diagnosis and current management of patients with MEN-1 ZES.
FAU - Simeone, D M
AU  - Simeone DM
AD  - Department of Surgery, University of Michigan, Ann Arbor 48109, USA. 
      Simeone@umich.edu
FAU - Scheiman, J M
AU  - Scheiman JM
FAU - Thompson, N W
AU  - Thompson NW
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Clin Gastroenterol
JT  - Journal of clinical gastroenterology
JID - 7910017
SB  - IM
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/diagnosis
MH  - Zollinger-Ellison Syndrome/*complications/diagnosis/*surgery
EDAT- 2001/03/14 10:00
MHDA- 2001/08/31 10:01
CRDT- 2001/03/14 10:00
PHST- 2001/03/14 10:00 [pubmed]
PHST- 2001/08/31 10:01 [medline]
PHST- 2001/03/14 10:00 [entrez]
AID - 10.1097/00004836-200103000-00022 [doi]
PST - ppublish
SO  - J Clin Gastroenterol. 2001 Mar;32(3):268-71. doi: 
      10.1097/00004836-200103000-00022.