PMID- 11246693
OWN - NLM
STAT- MEDLINE
DCOM- 20010614
LR  - 20071115
IS  - 0315-162X (Print)
IS  - 0315-162X (Linking)
VI  - 28
IP  - 2
DP  - 2001 Feb
TI  - Minimum clinically important difference: the crock of gold at the end of the 
      rainbow?
PG  - 439-44
AB  - The minimum clinically important difference (MCID), like the crock of gold at the 
      end of the rainbow, is attractive but unattainable. Empirical data on how 
      rheumatologists make clinical decisions show a wide variety of approaches and 
      lack of agreement in decision making. Clinical importance needs to consider the 
      magnitude of both the benefits and adverse events. A proposal for future attempts 
      to define MCID could explore links between short term changes in outcomes to 
      improvement in disability outcome many years later. Defining response to 
      treatment could be explored using different approaches and involving patients and 
      other professional groups.
FAU - Kirwan, J R
AU  - Kirwan JR
AD  - University of Bristol Division of Medicine, Bristol Royal Infirmary, UK. 
      John.Kirwan@Bristol.ac.uk
LA  - eng
PT  - Consensus Development Conference
PT  - Journal Article
PT  - Review
PL  - Canada
TA  - J Rheumatol
JT  - The Journal of rheumatology
JID - 7501984
SB  - IM
MH  - Clinical Trials as Topic
MH  - Diagnosis, Differential
MH  - Humans
MH  - Musculoskeletal Diseases/*diagnosis/*therapy
MH  - Observer Variation
MH  - Rheumatic Diseases/*diagnosis/*therapy
MH  - Treatment Outcome
RF  - 24
EDAT- 2001/03/15 10:00
MHDA- 2001/06/15 10:01
CRDT- 2001/03/15 10:00
PHST- 2001/03/15 10:00 [pubmed]
PHST- 2001/06/15 10:01 [medline]
PHST- 2001/03/15 10:00 [entrez]
PST - ppublish
SO  - J Rheumatol. 2001 Feb;28(2):439-44.