PMID- 11264545
OWN - NLM
STAT- MEDLINE
DCOM- 20010521
LR  - 20161124
IS  - 1071-9164 (Print)
IS  - 1071-9164 (Linking)
VI  - 7
IP  - 1
DP  - 2001 Mar
TI  - Radiographic measurements of cardiac size as predictors of outcome in patients 
      with dilated cardiomyopathy.
PG  - 13-20
AB  - BACKGROUND: Cardiac dilatation is a predictor of poor outcome in patients with 
      dilated cardiomyopathy. Whereas cardiac chamber dimensions or volumes can be 
      assessed by various noninvasive and invasive techniques, simple chest radiography 
      also may provide a valuable assessment of cardiac size. METHODS AND RESULTS: To 
      determine the relative power of radiographic heart measurements for predicting 
      outcome in dilated cardiomyopathy, we retrospectively studied 88 adult patients 
      with chest radiographs obtained within 35 days of echocardiography. Standard 
      radiographic variables were measured for each patient, and the cardiothoracic 
      (CT) ratio, frontal cardiac area, and volume were calculated. During a mean 
      4.1-year follow-up, 62 of the 88 (71%) patients died. CT ratio was the best 
      predictor of mortality among the radiographic cardiac measurements. By 
      multivariate analysis, a model including echocardiographic ejection fraction, New 
      York Heart Association (NYHA) functional class, and history of heart failure was 
      highly predictive of survival. When added to this model, CT ratio also was 
      independently associated with mortality, but not radiographic cardiac area or 
      volume. When radiographic variables were each added to CT ratio, they did not add 
      incremental predictive value to the model that included CT ratio alone. 
      Echocardiographic measurement of left ventricular (LV) size, especially when 
      indexed for body size, was independently predictive of outcome, but it did not 
      supersede the predictive power of CT ratio. CONCLUSION: The simply derived 
      radiographic CT ratio is a useful predictor of outcome in patients with dilated 
      cardiomyopathy and compares favorably with other clinical and selected 
      echocardiographic variables.
FAU - Ernst, E R
AU  - Ernst ER
AD  - Division of Cardiovascular Diseases and Internal Medicine, Section of 
      Biostatistics, Mayo Clinic, Rochester, Minnesota 55905, USA.
FAU - Shub, C
AU  - Shub C
FAU - Bailey, K R
AU  - Bailey KR
FAU - Brown, L R
AU  - Brown LR
FAU - Redfield, M M
AU  - Redfield MM
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - United States
TA  - J Card Fail
JT  - Journal of cardiac failure
JID - 9442138
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Cardiomyopathy, Dilated/*diagnostic imaging/*physiopathology
MH  - Female
MH  - Follow-Up Studies
MH  - Heart/anatomy & histology/*diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Prognosis
MH  - Radiography, Thoracic
MH  - Stroke Volume/*physiology
MH  - Surveys and Questionnaires
MH  - Survival Analysis
MH  - Ventricular Function, Left/*physiology
EDAT- 2001/03/27 10:00
MHDA- 2001/05/25 10:01
CRDT- 2001/03/27 10:00
PHST- 2001/03/27 10:00 [pubmed]
PHST- 2001/05/25 10:01 [medline]
PHST- 2001/03/27 10:00 [entrez]
AID - S1071-9164(01)34362-2 [pii]
AID - 10.1054/jcaf.2001.23244 [doi]
PST - ppublish
SO  - J Card Fail. 2001 Mar;7(1):13-20. doi: 10.1054/jcaf.2001.23244.