PMID- 11271300
OWN - NLM
STAT- MEDLINE
DCOM- 20010405
LR  - 20190915
IS  - 0934-0874 (Print)
IS  - 0934-0874 (Linking)
VI  - 7 Suppl 1
DP  - 1994
TI  - Selection of the most compatible graft recipient by computer program, used in 
      regional tissue typing laboratory of Hellas (R.T.T.L.).
PG  - S532-5
AB  - The purpose of this study was to present the new computer program that we 
      developed in the regional tissue typing laboratory (R.T.T.L.) and use for the 
      selection of the most suitable recipient for cadaveric allografts in a more 
      efficient way. This new program was written and compiled in TURBO PASCAL 6.0, 
      sorts all possible recipients to the HLA type of a donor, checks for the 
      existence of splits and utilises them, and when requested, gives out results to 
      more specific inquiries, i.e. all compatible recipients from 2DR2B2A to 1DR0B0A 
      matching. It can also forecast success percentages according to different 
      factors, i.e. combination of donor's and recipient's ages, HLA matching etc. The 
      material used for this study were the patients who are registered in the formal 
      cadaveric transplantation list of R.T.T.L. We have used this program since 2 
      January 1992 together with the old one. Since then we found that the new program 
      is faster in sorting all the possible recipients of cadaveric renal allografts 
      according to the criteria already mentioned. The total selection time, with all 
      the criteria activated, averages a few seconds, whereas with the old program it 
      took approximately 2 min just for the sorting of HLA matching, without any other 
      criteria activated. In the printout of the final result of each inquiry are all 
      the possible recipients in the sorted order together with relevant data 
      (telephone number, address etc.). As a result, the laboratory personnel has been 
      free from the tedious task of this sorting which was initially done by hand and 
      the possibility of error has been eliminated. The program was developed 
      exclusively by doctors and all the updates needed are done by the users. More 
      important, however, is the fact that in many cases the time of cold ischaemia was 
      reduced by more than 30 min with all the obvious advantages for the longevity of 
      the graft's life.
FAU - Kakas, P K
AU  - Kakas PK
AD  - Immunology Department, Thessaloniki, Greece.
FAU - Adam, K
AU  - Adam K
FAU - Lazidou, P
AU  - Lazidou P
FAU - Papakyriazi, H
AU  - Papakyriazi H
FAU - Parapanisiou, E
AU  - Parapanisiou E
FAU - Polymenides, Z
AU  - Polymenides Z
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Transpl Int
JT  - Transplant international : official journal of the European Society for Organ 
      Transplantation
JID - 8908516
RN  - 0 (ABO Blood-Group System)
SB  - IM
MH  - ABO Blood-Group System
MH  - Cadaver
MH  - Greece
MH  - Histocompatibility Testing/*methods
MH  - Humans
MH  - Kidney Transplantation/*immunology
MH  - Laboratories
MH  - *Patient Selection
MH  - Registries
MH  - Software
MH  - Tissue Donors
MH  - Tissue and Organ Procurement/organization & administration
EDAT- 1994/01/01 00:00
MHDA- 2001/04/06 10:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 2001/04/06 10:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 10.1111/j.1432-2277.1994.tb01436.x [doi]
PST - ppublish
SO  - Transpl Int. 1994;7 Suppl 1:S532-5. doi: 10.1111/j.1432-2277.1994.tb01436.x.