PMID- 11287807
OWN - NLM
STAT- MEDLINE
DCOM- 20010705
LR  - 20171101
IS  - 1016-2291 (Print)
IS  - 1016-2291 (Linking)
VI  - 34
IP  - 2
DP  - 2001 Feb
TI  - Supratentorial ependymoma in children.
PG  - 77-87
AB  - The clinical and pathological characteristics of supratentorial ependymomas (STE) 
      in children are not well identified in the literature, because most series deal 
      with ependymomas regardless of their location or the age of the patient. As a 
      result, the pathological description of the disorder is still debated. We 
      therefore reviewed our cases of children operated for STE and compared them with 
      cases of infratentorial ependymomas (ITE) to provide a better characterization of 
      STE and suggest guidelines for treatment. From 1985 to 1999, we operated 18 
      children for STE, almost half of which developed with no connection to the 
      ventricular system. Intraoperative bleeding and infiltration of the basal ganglia 
      prevented total removal in 4 cases and were the main causes of operative 
      mortality and morbidity. The 5-year overall survival and recurrence-free survival 
      rates were 54 and 37%, respectively, and were highly affected by the extent of 
      resection, but not by histological grade. Because of the high recurrence rate, we 
      recommend systematic postoperative irradiation limited to the tumor site for all 
      high-grade tumors in older children, and reoperation after subtotal removal and 
      for recurrences.
CI  - Copyright 2001 S. Karger AG, Basel
FAU - Vinchon, M
AU  - Vinchon M
AD  - Services de Neurochirurgie Pediatrique, CHRU de Lille, France. 
      m-vinchon@chru-lille.fr
FAU - Soto-Ares, G
AU  - Soto-Ares G
FAU - Riffaud, L
AU  - Riffaud L
FAU - Ruchoux, M M
AU  - Ruchoux MM
FAU - Dhellemmes, P
AU  - Dhellemmes P
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Pediatr Neurosurg
JT  - Pediatric neurosurgery
JID - 9114967
SB  - IM
MH  - Adolescent
MH  - Brain/pathology
MH  - Chemotherapy, Adjuvant
MH  - Child
MH  - Child, Preschool
MH  - Combined Modality Therapy
MH  - Ependymoma/diagnosis/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Infant
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Postoperative Complications/diagnosis/surgery
MH  - Radiography
MH  - Radiotherapy, Adjuvant
MH  - Reoperation
MH  - Stereotaxic Techniques
MH  - Supratentorial Neoplasms/diagnosis/diagnostic imaging/drug therapy/*surgery
EDAT- 2001/04/05 10:00
MHDA- 2001/07/06 10:01
CRDT- 2001/04/05 10:00
PHST- 2001/04/05 10:00 [pubmed]
PHST- 2001/07/06 10:01 [medline]
PHST- 2001/04/05 10:00 [entrez]
AID - 55999 [pii]
AID - 10.1159/000055999 [doi]
PST - ppublish
SO  - Pediatr Neurosurg. 2001 Feb;34(2):77-87. doi: 10.1159/000055999.