PMID- 11302460
OWN - NLM
STAT- MEDLINE
DCOM- 20010816
LR  - 20191025
IS  - 0342-5282 (Print)
IS  - 0342-5282 (Linking)
VI  - 24
IP  - 1
DP  - 2001 Mar
TI  - Sensitivity of qualitative and quantitative spasticity measures to clinical 
      treatment with cryotherapy.
PG  - 15-24
AB  - This study examined the extent to which a battery of tests could detect a 
      reduction of plantarflexor spasticity resulting from cryotherapy. The tests 
      included a traditional qualitative spasticity scale, three potential quantitative 
      spasticity measures and a measure of voluntary ankle muscle function. Twenty-six 
      adult traumatic-brain-injured subjects were examined; these included 22 males and 
      4 females. The mean age was 28.15 years (range: 18-57, SD 10.78). The five tests 
      were performed in random sequence on both ankles of each subject, before and 
      after a 20 minute cold pack application to the calf. Tests were: modified 
      Ashworth scale (MAS) scoring; H-reflex testing with and without dorsiflexor 
      contraction (Hdf/Hctrl ratio); H-reflex testing with and without Achilles tendon 
      vibration (Hvib/Hctrl ratio); reflex threshold angle (RTA) and timed toe tapping 
      (TIT). Cryotherapy resulted in lowered MAS scores consistent with a reduction in 
      spasticity. Doubly multivariate repeated measures ANOVA revealed a significant 
      difference (F = 24.16, P < 0.001) in test scores between the pre- and 
      post-cryotherapy test batteries. Significant pre- and post-cryotherapy 
      differences (P < or = 0.03) for all dependent measures contributed to the main 
      effect for cryotherapy. However, among the potential quantitative measures of 
      spasticity only the RTA test demonstrated appropriate sensitivity to the 
      reduction in spasticity. In spite of spasticity reduction, TIT performance was 
      impaired following muscle cooling. Failure of the H-reflex ratios to show a 
      reduction consistent with reduced spasticity was attributed to competing alpha 
      and gamma motoneuron effects resulting from peripheral cooling.
FAU - Allison, S C
AU  - Allison SC
AD  - Academy of Health Sciences, Fort Sam Houston, TX 78234, USA.
FAU - Abraham, L D
AU  - Abraham LD
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Int J Rehabil Res
JT  - International journal of rehabilitation research. Internationale Zeitschrift fur 
      Rehabilitationsforschung. Revue internationale de recherches de readaptation
JID - 7805421
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Ankle
MH  - Brain Injuries/complications
MH  - *Cryotherapy
MH  - Female
MH  - H-Reflex
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Muscle Spasticity/*diagnosis/etiology/*rehabilitation
MH  - *Reflex
MH  - Sensitivity and Specificity
MH  - Treatment Outcome
EDAT- 2001/04/17 10:00
MHDA- 2001/08/17 10:01
CRDT- 2001/04/17 10:00
PHST- 2001/04/17 10:00 [pubmed]
PHST- 2001/08/17 10:01 [medline]
PHST- 2001/04/17 10:00 [entrez]
AID - 10.1097/00004356-200103000-00003 [doi]
PST - ppublish
SO  - Int J Rehabil Res. 2001 Mar;24(1):15-24. doi: 10.1097/00004356-200103000-00003.