PMID- 11306230 OWN - NLM STAT- MEDLINE DCOM- 20011207 LR - 20220309 IS - 0749-3797 (Print) IS - 0749-3797 (Linking) VI - 20 IP - 3 Suppl DP - 2001 Apr TI - The art and science of incorporating cost effectiveness into evidence-based recommendations for clinical preventive services. PG - 36-43 AB - As medical technology continues to expand and the cost of using all effective clinical services exceeds available resources, decisions about health care delivery may increasingly rely on assessing the cost-effectiveness of medical services. Cost-effectiveness is particularly relevant for decisions about how to implement preventive services, because these decisions typically represent major investments in the future health of large populations. As such, decisions regarding the implementation of preventive services frequently involve, implicitly if not explicitly, consideration of costs. Cost-effectiveness analysis summarizes the expected benefits, harms, and costs of alternative strategies to improve health and has become an important tool for explicitly incorporating economic considerations into clinical decision making. Acknowledging the usefulness of this tool, the third U.S. Preventive Services Task Force (USPSTF) has initiated a process for systematically reviewing cost-effectiveness analyses as an aid in making recommendations about clinical preventive services. In this paper, we provide an overview and examples of roles for using cost-effectiveness analyses to inform preventive services recommendations, discuss limitations of cost-effectiveness data in shaping evidence-based preventive health care policies, outline the USPSTF approach to using cost-effectiveness analyses, and discuss the methods the USPSTF is developing to assess the quality and results of cost-effectiveness studies. While this paper focuses on clinical preventive services (i.e., screening, counseling, immunizations, and chemoprevention), the framework we have developed should be broadly portable to other health care services. FAU - Saha, S AU - Saha S AD - Evidence-Based Practice Center, Oregon Health Sciences University, Portland, Oregon, USA. sahas@ohsu.edu FAU - Hoerger, T J AU - Hoerger TJ FAU - Pignone, M P AU - Pignone MP FAU - Teutsch, S M AU - Teutsch SM FAU - Helfand, M AU - Helfand M FAU - Mandelblatt, J S AU - Mandelblatt JS CN - Cost Work Group, Third US Preventive Services Task Force LA - eng GR - 290-97-0011/PHS HHS/United States GR - 290-97-0018/PHS HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Research Support, U.S. Gov't, P.H.S. PL - Netherlands TA - Am J Prev Med JT - American journal of preventive medicine JID - 8704773 SB - IM MH - Advisory Committees MH - *Cost-Benefit Analysis MH - Delivery of Health Care/economics MH - Evidence-Based Medicine/*economics MH - Humans MH - Models, Economic MH - Preventive Health Services/*economics MH - United States MH - United States Agency for Healthcare Research and Quality EDAT- 2001/04/18 10:00 MHDA- 2002/01/05 10:01 CRDT- 2001/04/18 10:00 PHST- 2001/04/18 10:00 [pubmed] PHST- 2002/01/05 10:01 [medline] PHST- 2001/04/18 10:00 [entrez] AID - S0749379701002604 [pii] AID - 10.1016/s0749-3797(01)00260-4 [doi] PST - ppublish SO - Am J Prev Med. 2001 Apr;20(3 Suppl):36-43. doi: 10.1016/s0749-3797(01)00260-4.