PMID- 11316508
OWN - NLM
STAT- MEDLINE
DCOM- 20010705
LR  - 20190831
IS  - 0022-3999 (Print)
IS  - 0022-3999 (Linking)
VI  - 50
IP  - 3
DP  - 2001 Mar
TI  - The effects of homeopathic belladonna 30CH in healthy volunteers -- a randomized, 
      double-blind experiment.
PG  - 155-60
AB  - OBJECTIVES: The practice of homeopathy rests on symptoms, which have been 
      produced by medicinal substances in healthy volunteers, often applied at 
      ultramolecular dilutions. It is unknown whether these symptom patterns are due to 
      specific effects or chance fluctuation. METHODS: We tested the hypothesis that a 
      homeopathic substance can bring about symptoms different from observation and 
      placebo in a double-blind, placebo-controlled crossover design with baseline 
      observation. RESULTS: 87 out of 118 healthy volunteers took both placebo and 
      homeopathic belladonna 30CH in random sequence, after a 2-week observation 
      period, and finished the 8-week trial. Apart from an insignificant tendency for 
      subjects to report more symptoms with belladonna (mean number: 27.34), as 
      compared to observation (24.26) or placebo (24.17), there was no indication that 
      subjects reacted differently to homeopathy than to placebo or during baseline. 
      CONCLUSION: There is no indication that belladonna 30CH produces symptoms 
      different from placebo or from no intervention. Symptoms of a homeopathic 
      pathogenetic trial (HPT) are most likely chance fluctuations.
FAU - Walach, H
AU  - Walach H
AD  - Department of Environmental Medicine and Hygiene, University Hospital, Freiburg, 
      Germany. walach@ukl.uni-freiburg.de
FAU - Koster, H
AU  - Koster H
FAU - Hennig, T
AU  - Hennig T
FAU - Haag, G
AU  - Haag G
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Psychosom Res
JT  - Journal of psychosomatic research
JID - 0376333
RN  - 0 (Materia Medica)
SB  - IM
MH  - Adult
MH  - Atropa belladonna/*therapeutic use
MH  - Cross-Over Studies
MH  - Dose-Response Relationship, Drug
MH  - Double-Blind Method
MH  - Female
MH  - Germany
MH  - Homeopathy/*standards
MH  - Humans
MH  - Male
MH  - Materia Medica/*pharmacology
MH  - Middle Aged
MH  - *Phytotherapy
MH  - *Plants, Medicinal
MH  - *Plants, Toxic
MH  - Reference Values
MH  - Treatment Outcome
EDAT- 2001/04/24 10:00
MHDA- 2001/07/06 10:01
CRDT- 2001/04/24 10:00
PHST- 2001/04/24 10:00 [pubmed]
PHST- 2001/07/06 10:01 [medline]
PHST- 2001/04/24 10:00 [entrez]
AID - S0022-3999(00)00224-5 [pii]
AID - 10.1016/s0022-3999(00)00224-5 [doi]
PST - ppublish
SO  - J Psychosom Res. 2001 Mar;50(3):155-60. doi: 10.1016/s0022-3999(00)00224-5.