PMID- 11323543
OWN - NLM
STAT- MEDLINE
DCOM- 20010621
LR  - 20220316
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 33
IP  - 5
DP  - 2001 May
TI  - Blood and urinary measures of hydration status during progressive acute 
      dehydration.
PG  - 747-53
AB  - PURPOSE: To determine whether: a) plasma osmolarity (Posm) is sensitive to small 
      incremental changes in hydration status, b) urine specific gravity (Usg) can 
      accurately identify a state of euhydration, c) Usg is a sensitive indicator of a 
      change in hydration status, and d) Usg correlates with Posm. METHODS: Euhydrated 
      (Posm = 288 +/- 4 mOsm.L-1) subjects (N = 12) were dehydrated by 5% of their body 
      weight via exercise in the heat (40 degrees C, 20% RH). Posm, urine osmolarity 
      (Uosm), and Usg were measured at 1%, 3%, and 5% dehydration, and 30 and 60 min of 
      recovery (rec). Subjects consumed water in recovery equal to their loss of body 
      weight. RESULTS: Posm increased incrementally with each successive increase in 
      percent body weight loss (%BWL). Usg was not significantly different from 
      baseline until 3% BML. Uosm was not significantly different from baseline until 
      5% BWL. Usg correlated moderately (r = 0.46, P > 0.10) with Posm but reasonably 
      well (r = 0.68, P < 0.02) with Uosm. CONCLUSIONS: Posm accurately identifies a 
      state of euhydration and is sensitive to changes in hydration status during acute 
      dehydration and rehydration. Usg and Uosm are also sensitive to changes in 
      hydration status but lag behind during periods of rapid body fluid turnover and 
      therefore correlate only moderately with Posm during acute dehydration.
FAU - Popowski, L A
AU  - Popowski LA
AD  - Department of Exercise Science, University of Iowa, Iowa City, IA 52242, USA.
FAU - Oppliger, R A
AU  - Oppliger RA
FAU - Patrick Lambert, G
AU  - Patrick Lambert G
FAU - Johnson, R F
AU  - Johnson RF
FAU - Kim Johnson, A
AU  - Kim Johnson A
FAU - Gisolf, C V
AU  - Gisolf CV
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Reagent Strips)
SB  - IM
MH  - Adult
MH  - Dehydration/*physiopathology
MH  - *Exercise
MH  - Humans
MH  - Male
MH  - Osmolar Concentration
MH  - Reagent Strips
MH  - Sensitivity and Specificity
MH  - Urinalysis
MH  - Water-Electrolyte Balance
OTO - NASA
OT  - Non-programmatic
EDAT- 2001/04/27 10:00
MHDA- 2001/06/22 10:01
CRDT- 2001/04/27 10:00
PHST- 2001/04/27 10:00 [pubmed]
PHST- 2001/06/22 10:01 [medline]
PHST- 2001/04/27 10:00 [entrez]
AID - 10.1097/00005768-200105000-00011 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2001 May;33(5):747-53. doi: 
      10.1097/00005768-200105000-00011.