PMID- 11324499 OWN - NLM STAT- MEDLINE DCOM- 20010517 LR - 20161020 IS - 1001-9294 (Print) IS - 1001-9294 (Linking) VI - 12 IP - 2 DP - 1997 Jun TI - Detection of human herpesvirus 6(HHV-6) DNA in salivary glands by the polymerase chain reaction. PG - 126-8 AB - To assess the presence of HHV-6-Specific DNA in human salivary glands, eighteen specimens of salivary gland tissue were investigated using the polymerase chain reaction. Eight of nine parotid glands, five of seven submandibular glands and one of two sublingual glands were found to have amplification of the HHV-6-specific sequence. The findings suggest that salivary gland tissue is one of the potential sites for HHV-6 persistence following primary infection and that saliva is a vehicle for transmission of the virus. FAU - Zhao, J AU - Zhao J AD - Department of Stomatology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730. FAU - Fan, H AU - Fan H FAU - Mu, G AU - Mu G FAU - Shen, X AU - Shen X FAU - Cheng, X AU - Cheng X LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - China TA - Chin Med Sci J JT - Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih JID - 9112559 RN - 0 (DNA, Viral) SB - IM MH - DNA, Viral/*analysis MH - Herpesviridae Infections MH - Herpesvirus 6, Human/*isolation & purification MH - Humans MH - Parotid Neoplasms/virology MH - Polymerase Chain Reaction MH - Salivary Gland Calculi/virology MH - Salivary Glands/*virology MH - Sialadenitis/virology EDAT- 1997/06/01 00:00 MHDA- 2001/05/18 10:01 CRDT- 1997/06/01 00:00 PHST- 1997/06/01 00:00 [pubmed] PHST- 2001/05/18 10:01 [medline] PHST- 1997/06/01 00:00 [entrez] PST - ppublish SO - Chin Med Sci J. 1997 Jun;12(2):126-8.