PMID- 11341077
OWN - NLM
STAT- MEDLINE
DCOM- 20010927
LR  - 20190726
IS  - 0147-8389 (Print)
IS  - 0147-8389 (Linking)
VI  - 24
IP  - 4 Pt 1
DP  - 2001 Apr
TI  - Implantation of a dual chamber pacing and sensing single pass defibrillation 
      lead.
PG  - 416-23
AB  - Dual-chamber ICDs are increasingly used to avoid inappropriate shocks due to 
      supraventricular tachycardias. Additionally, many ICD patients will probably 
      benefit from dual chamber pacing. The purpose of this pilot study was to evaluate 
      the intraoperative performance and short-term follow-up of an innovative single 
      pass right ventricular defibrillation lead capable of bipolar sensing and pacing 
      in the right atrium and ventricle. Implantation of this single pass right 
      ventricular defibrillation lead was successful in all 13 patients (age 63 +/- 8 
      years; LVEF 0.44 +/- 0.16; New York Heart Association [NYHA] 2.4 +/- 0.4, 
      previous open heart surgery in all patients). The operation time was 79 +/- 29 
      minutes, the fluoroscopy time 4.7 +/- 3.1 minutes. No perioperative complications 
      occurred. The intraoperative atrial sensing was 1.7 +/- 0.5 mV, the atrial pacing 
      threshold product was 0.20 +/- 0.14 V/ms (range 0.03-0.50 V/ms). The 
      defibrillation threshold was 8.8 +/- 2.7 J. At prehospital discharge and at 
      1-month and 3-month follow-up, atrial sensing was 1.9 +/- 0.9, 2.1 +/- 0.5, and 
      2.7 +/- 0.6 mV, respectively, (P = NS, P < 0.05, P < 0.05 to implant, 
      respectively), the mean atrial threshold product 0.79, 1.65, and 1.29 V/ms, 
      respectively. In two patients, an intermittent exit block occurred in different 
      body postures. All spontaneous and induced ventricular arrhythmias were detected 
      and terminated appropriately. Thus, in a highly selected patient group, atrial 
      and ventricular sensing and pacing with a single lead is possible under 
      consideration of an atrial pacing dysfunction in 17% of patients.
FAU - Gradaus, R
AU  - Gradaus R
AD  - Westfalische Wilhelms-University Munster, Department of Cardiology and Angiology 
      and Institute for Arteriosclerosis Research, Munster, Germany.
FAU - Block, M
AU  - Block M
FAU - Dorszewski, A
AU  - Dorszewski A
FAU - Schriever, C
AU  - Schriever C
FAU - Hammel, D
AU  - Hammel D
FAU - Scheld, H H
AU  - Scheld HH
FAU - Borggrefe, M
AU  - Borggrefe M
FAU - Breithardt, G
AU  - Breithardt G
FAU - Bocker, D
AU  - Bocker D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Pacing Clin Electrophysiol
JT  - Pacing and clinical electrophysiology : PACE
JID - 7803944
SB  - IM
MH  - Aged
MH  - *Defibrillators, Implantable
MH  - Electrocardiography/*instrumentation
MH  - *Electrodes, Implanted
MH  - Equipment Design
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Atria/physiopathology
MH  - Heart Ventricles/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Pacemaker, Artificial
MH  - Tachycardia, Supraventricular/physiopathology/*therapy
MH  - Ventricular Fibrillation/physiopathology/*therapy
EDAT- 2001/05/09 10:00
MHDA- 2001/09/28 10:01
CRDT- 2001/05/09 10:00
PHST- 2001/05/09 10:00 [pubmed]
PHST- 2001/09/28 10:01 [medline]
PHST- 2001/05/09 10:00 [entrez]
AID - 10.1046/j.1460-9592.2001.00416.x [doi]
PST - ppublish
SO  - Pacing Clin Electrophysiol. 2001 Apr;24(4 Pt 1):416-23. doi: 
      10.1046/j.1460-9592.2001.00416.x.