PMID- 11359535
OWN - NLM
STAT- MEDLINE
DCOM- 20010726
LR  - 20190815
IS  - 0953-816X (Print)
IS  - 0953-816X (Linking)
VI  - 13
IP  - 9
DP  - 2001 May
TI  - Modulation of dendrodendritic interactions and mitral cell excitability in the 
      mouse accessory olfactory bulb by vaginocervical stimulation.
PG  - 1833-8
AB  - When female mice are mated, they form a memory to the pheromonal signal of their 
      male partner. The neural changes underlying this memory occur in the accessory 
      olfactory bulb, depend upon vaginocervical stimulation at mating and involve 
      changes at the reciprocal synapses between mitral and granule cells. However, the 
      action of vaginocervical stimulation on the reciprocal interactions between 
      mitral and granule cells remains to be elucidated. We have examined the effects 
      of vaginocervical stimulation on paired-pulse depression of amygdala-evoked field 
      potentials recorded in the external plexiform layer of the accessory olfactory 
      bulb (AOB) and the single-unit activity of mitral cells antidromically stimulated 
      from the amygdala in urethane-anaesthetized female mice. Artificial 
      vaginocervical stimulation reduced paired-pulse depression (considered to be due 
      to feedback inhibition of the mitral cell dendrites from the granule cells via 
      reciprocal dendrodendritic synapses) recorded in the AOB external plexiform 
      layer. As would be expected from this result, vaginocervical stimulation also 
      enhanced the spontaneous activity of a proportion of the mitral cells tested. 
      These results suggest that vaginocervical stimulation reduces dendrodendritic 
      feedback inhibition to mitral cells and enhances their activity.
FAU - Otsuka, T
AU  - Otsuka T
AD  - Department of Veterinary Physiology, Faculty of Agriculture, Kagoshima 
      University, Kagoshima 890-0065, Japan.
FAU - Ishii, K
AU  - Ishii K
FAU - Osako, Y
AU  - Osako Y
FAU - Okutani, F
AU  - Okutani F
FAU - Taniguchi, M
AU  - Taniguchi M
FAU - Oka, T
AU  - Oka T
FAU - Kaba, H
AU  - Kaba H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - France
TA  - Eur J Neurosci
JT  - The European journal of neuroscience
JID - 8918110
RN  - 0 (Sex Attractants)
SB  - IM
MH  - Action Potentials/physiology
MH  - Amygdala/cytology/physiology
MH  - Animals
MH  - Cervix Uteri/innervation/physiology
MH  - Dendrites/*physiology/ultrastructure
MH  - Electric Stimulation
MH  - Evoked Potentials/physiology
MH  - Feedback/physiology
MH  - Female
MH  - Memory/*physiology
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Neural Inhibition/physiology
MH  - Olfactory Bulb/cytology/*physiology
MH  - Physical Stimulation
MH  - Sex Attractants/*metabolism
MH  - Sexual Behavior, Animal/physiology
MH  - Smell/*physiology
MH  - Synapses/*physiology/ultrastructure
MH  - Synaptic Transmission/*physiology
MH  - Vagina/innervation/physiology
MH  - Visceral Afferents/physiology
MH  - Vomeronasal Organ/physiology
EDAT- 2001/05/22 10:00
MHDA- 2001/07/28 10:01
CRDT- 2001/05/22 10:00
PHST- 2001/05/22 10:00 [pubmed]
PHST- 2001/07/28 10:01 [medline]
PHST- 2001/05/22 10:00 [entrez]
AID - ejn1557 [pii]
AID - 10.1046/j.0953-816x.2001.01557.x [doi]
PST - ppublish
SO  - Eur J Neurosci. 2001 May;13(9):1833-8. doi: 10.1046/j.0953-816x.2001.01557.x.