PMID- 11402256
OWN - NLM
STAT- MEDLINE
DCOM- 20010726
LR  - 20191104
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 11
IP  - 2
DP  - 2001 Jun
TI  - The effect of low-carbohydrate diet on the pattern of hormonal changes during 
      incremental, graded exercise in young men.
PG  - 248-57
AB  - The purpose of this study was to discover whether severe dietary carbohydrate 
      (CHO) restriction modifies the relationship between exercise intensity and 
      hormonal responses to exercise. Changes in the plasma adrenaline (A), 
      noradrenaline (NA), growth hormone (hGH), testosterone (T), and blood lactate 
      (LA) during an incremental exercise performed until volitional exhaustion were 
      determined in 8 physically active volunteers after 3 days on low CHO (< 5% of 
      energy content; L-CHO) and isocaloric mixed (M) diets. Following L-CHO diet, the 
      basal plasma A, NA, and hGH concentrations were increased, whilst T and LA levels 
      were decreased. During exercise all the hormones increased exponentially, with 
      thresholds close to that of LA. Neither the magnitude nor the pattern of the 
      hormonal changes were affected by L-CHO diet except the NA threshold, which was 
      lowered. Blood LA response to exercise was diminished and LA threshold was 
      shifted towards higher loads by L-CHO diet. It is concluded that restriction of 
      CHO intake (a) does not affect the pattern of changes in plasma A, hGH, and T 
      concentrations during graded exercise but lowers NA threshold, indicating 
      increased sensitivity of the sympathetic nervous system to exercise stimulus; (b) 
      alters the basal and exercise levels of circulating hormones, which may have an 
      impact on the balance between anabolic and catabolic processes and subsequently 
      influence the effectiveness of training.
FAU - Langfort, J L
AU  - Langfort JL
AD  - Department of Applied Physiology, Medical Research Centre, Polish Academy of 
      Sceinces, 5 Pawinskiego Str., PL-02-106 Warsaw, Poland.
FAU - Zarzeczny, R
AU  - Zarzeczny R
FAU - Nazar, K
AU  - Nazar K
FAU - Kaciuba-Uscilko, H
AU  - Kaciuba-Uscilko H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 12629-01-5 (Human Growth Hormone)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 3XMK78S47O (Testosterone)
RN  - X4W3ENH1CV (Norepinephrine)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
MH  - Adult
MH  - Anaerobic Threshold
MH  - Dietary Carbohydrates/*administration & dosage/pharmacology
MH  - Epinephrine/*blood/metabolism
MH  - Exercise/*physiology
MH  - Human Growth Hormone/*blood/metabolism
MH  - Humans
MH  - Lactic Acid/*blood/metabolism
MH  - Male
MH  - Norepinephrine/*blood/metabolism
MH  - Testosterone/*blood/metabolism
EDAT- 2001/06/13 10:00
MHDA- 2001/07/28 10:01
CRDT- 2001/06/13 10:00
PHST- 2001/06/13 10:00 [pubmed]
PHST- 2001/07/28 10:01 [medline]
PHST- 2001/06/13 10:00 [entrez]
AID - 10.1123/ijsnem.11.2.248 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2001 Jun;11(2):248-57. doi: 
      10.1123/ijsnem.11.2.248.