PMID- 11411720
OWN - NLM
STAT- MEDLINE
DCOM- 20010712
LR  - 20200317
IS  - 1466-5026 (Print)
IS  - 1466-5026 (Linking)
VI  - 51
IP  - Pt 3
DP  - 2001 May
TI  - Treponema parvum sp. nov., a small, glucoronic or galacturonic acid-dependent 
      oral spirochaete from lesions of human periodontitis and acute necrotizing 
      ulcerative gingivitis.
PG  - 955-962
LID - 10.1099/00207713-51-3-955 [doi]
AB  - Small oral spirochaetes with a strict dependence on either glucuronic acid (GluA) 
      or galacturonic acid (GalA) were isolated from European patients with 
      periodontitis and from Chinese patients with either gingivitis or acute 
      necrotizing ulcerative gingivitis (ANUG). Thirteen such isolates were similar 
      phenotypically to Treponema pectinovorum ATCC 33768T and this classification was 
      confirmed by 16S rRNA sequencing. However, four isolates differed from T. 
      pectinovorum by their small cell size, by a prominent beta-glucuronidase 
      activity, by a distinct protein and antigen profile, by an inability to grow on 
      pectin as sole source of carbohydrate and by a markedly enhanced growth rate when 
      supplied with a second carbohydrate (L-arabinose, D-galactose, D-glucose, 
      D-fructose, D-mannitol, D-mannose, pectin, D-ribose or D-xylose) in addition to 
      the essential GluA/GalA. By 16S rRNA sequencing these four isolates clustered in 
      the recently described phylotype 'Smibert-2'. T. pectinovorum (14 strains) and 
      'Smibert-2' (four isolates with beta-glucuronidase activity) could each be 
      subdivided into two serotypes based on immunoblot reactivity with two mAbs. 
      Representatives of the two groups, including T. pectinovorum ATCC 33768T, showed 
      a 1:2:1-type periplasmic flagellar arrangement. 'Smibert-2' is described as a 
      novel species, Treponema parvum sp. nov., with isolate OMZ 833T (= ATCC 700770T) 
      proposed as the type strain and OMZ 842 (= ATCC 700773) as reference strain for a 
      second serotype.
FAU - Wyss, C
AU  - Wyss C
FAU - Dewhirst, F E
AU  - Dewhirst FE
FAU - Gmur, R
AU  - Gmur R
FAU - Thurnheer, T
AU  - Thurnheer T
FAU - Xue, Y
AU  - Xue Y
FAU - Schupbach, P
AU  - Schupbach P
FAU - Guggenheim, B
AU  - Guggenheim B
FAU - Paster, B J
AU  - Paster BJ
LA  - eng
SI  - GENBANK/AF302937
SI  - GENBANK/AF302938
GR  - DE-10374/DE/NIDCR NIH HHS/United States
GR  - DE-11443/DE/NIDCR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Int J Syst Evol Microbiol
JT  - International journal of systematic and evolutionary microbiology
JID - 100899600
RN  - 0 (DNA, Ribosomal)
RN  - 0 (Enzymes)
RN  - 0 (Hexuronic Acids)
RN  - 0 (RNA, Ribosomal, 16S)
RN  - 4JK6RN80GF (galacturonic acid)
RN  - 8A5D83Q4RW (Glucuronic Acid)
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - DNA, Ribosomal/genetics
MH  - Dental Plaque/*microbiology
MH  - Enzymes/analysis
MH  - Female
MH  - Gingivitis, Necrotizing Ulcerative/*microbiology
MH  - Glucuronic Acid/*metabolism
MH  - Hexuronic Acids/*metabolism
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Molecular Sequence Data
MH  - Periodontitis/*microbiology
MH  - Phenotype
MH  - *Phylogeny
MH  - RNA, Ribosomal, 16S/genetics
MH  - Treponema/*classification/isolation & purification/physiology/ultrastructure
MH  - Treponemal Infections/*microbiology
EDAT- 2001/06/20 10:00
MHDA- 2001/07/13 10:01
CRDT- 2001/06/20 10:00
PHST- 2001/06/20 10:00 [pubmed]
PHST- 2001/07/13 10:01 [medline]
PHST- 2001/06/20 10:00 [entrez]
AID - 10.1099/00207713-51-3-955 [doi]
PST - ppublish
SO  - Int J Syst Evol Microbiol. 2001 May;51(Pt 3):955-962. doi: 
      10.1099/00207713-51-3-955.