PMID- 11414430 OWN - NLM STAT- MEDLINE DCOM- 20011025 LR - 20041117 IS - 0125-1562 (Print) IS - 0125-1562 (Linking) VI - 31 IP - 4 DP - 2000 Dec TI - Leptin concentration in relation to body mass index (BMI) and hematological measurements in Thai obese and overweight subjects. PG - 787-94 AB - The weight, height and body mass index (BMI), including waist/hip ratio, serum leptin and hematological parameters of 48 male and 166 female overweight (BMI > or = 25.00) Thai volunteers who came for a physical check-up at the Out-patient Department, General Practice Section, Rajvithi Hospital, Bangkok during the period March-October 1998, were investigated. There were statistically significantly higher levels of serum leptin, mean corpuscular mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) in the overweight than in the control subjects. The median serum leptin concentration in overweight subjects was 19.6 (2.0-60.0 ng/ml) compared with 9.0 (range 1.0-30.0 ng/ml) in the control subjects (p < 0.001). The medians of leptin in overweight and obese males were significantly higher than those of overweight and obese females. 66.7% (32 out of 48) of overweight and obese males were found to have elevated leptin levels, while 87.3% (145 out of 166) were found in overweight and obese females. Anemia was found in 18.7% of female overweight and obese subjects, using hemoglobin as an indicator. Significant associations were found between weight, height, BMI, waist, hip, waist/hip ratio, hemoglobin, hematocrit, and serum leptin in both male and female overweight subjects. A negative correlation was found between serum leptin and hemoglobin, and hematocrit in both overweight and obese subjects. FAU - Tungtrongchitr, R AU - Tungtrongchitr R AD - Department of Tropical Nutrition and Food Science, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. FAU - Pongpaew, P AU - Pongpaew P FAU - Phonrat, B AU - Phonrat B FAU - Tribunyatkul, S AU - Tribunyatkul S FAU - Viroonudomphol, D AU - Viroonudomphol D FAU - Supawan, V AU - Supawan V FAU - Jintaridhi, P AU - Jintaridhi P FAU - Lertchavanakul, A AU - Lertchavanakul A FAU - Vudhivai, N AU - Vudhivai N FAU - Schelp, F P AU - Schelp FP LA - eng PT - Journal Article PL - Thailand TA - Southeast Asian J Trop Med Public Health JT - The Southeast Asian journal of tropical medicine and public health JID - 0266303 RN - 0 (Hemoglobins) RN - 0 (Leptin) SB - IM MH - Adolescent MH - Adult MH - *Body Mass Index MH - Case-Control Studies MH - Female MH - *Hematocrit MH - Hemoglobins/*analysis MH - Humans MH - Leptin/*blood MH - Male MH - Middle Aged MH - Obesity/*blood MH - Thailand EDAT- 2001/06/21 10:00 MHDA- 2001/10/26 10:01 CRDT- 2001/06/21 10:00 PHST- 2001/06/21 10:00 [pubmed] PHST- 2001/10/26 10:01 [medline] PHST- 2001/06/21 10:00 [entrez] PST - ppublish SO - Southeast Asian J Trop Med Public Health. 2000 Dec;31(4):787-94.