PMID- 11414603
OWN - NLM
STAT- MEDLINE
DCOM- 20011025
LR  - 20190921
IS  - 0886-0440 (Print)
IS  - 0886-0440 (Linking)
VI  - 15
IP  - 3
DP  - 2000 May-Jun
TI  - Partial left ventriculectomy: overall and late results in 44 class IV patients 
      with 4-year follow-up.
PG  - 179-85
AB  - BACKGROUND: This study reports long-term results of partial left ventriculectomy 
      (PLV). METHODS: Forty-four patients with dilated cardiomyopathy were operated on 
      in a 4-year study. Echocardiograms, catheterization, and stress tests with oxygen 
      consumption (VO2) were performed. RESULTS: The survivors' preoperative ejection 
      fractions of 22.1% +/- 4.9% improved to 30.9% +/- 9.4%, left ventricular (LV) 
      end-diastolic diameter decreased from 79.4 +/- 9.3 mm to 61.9 +/- 8.2 mm, and 
      maximum VO2 consumption improved from 8.8 +/- 3.9 mL/kg per minute to 15.8 +/- 
      6.1 mL/kg per minute at 22.6 months. These data also showed improvements in 
      nonsurviving patients, according to the last evaluation before death. Seven of 12 
      survivors (58.3%) were in New York Heart Association (NYHA) I and II in December 
      1998. Twelve patients had elevated pulmonary vascular resistance (PVR) 
      contraindicating heart transplant. In five patients the PVR returned to normal 
      and one high-PVR patient was transplanted at the 16th postoperative month. 
      Survival was 56.8%, 47.7%, 38.4%, and 35.9%, respectively, at 3, 6, 12, and 18 
      months, with a tendency to stabilize at 32.7% thereafter. Arrhythmias and heart 
      failure were the main causes of death. CONCLUSIONS: In spite of improvement of 
      ventricular function and quality of life of the survivors, high mortality is a 
      limiting factor. PLV can be indicated as a bridge to heart transplantation in 
      high-PVR patients or if ventricular assist devices or donor hearts are not 
      available.
FAU - Lucchese, F A
AU  - Lucchese FA
AD  - Sao Francisco Hospital at Complexo Hospitalar da Santa Casa, Porto Alegre, RS, 
      Brazil.
FAU - Frota Filho, J D
AU  - Frota Filho JD
FAU - Blacher, C
AU  - Blacher C
FAU - Pereira, W
AU  - Pereira W
FAU - Lucio, E
AU  - Lucio E
FAU - Beck, L
AU  - Beck L
FAU - Leonetti, L A
AU  - Leonetti LA
FAU - Leaes, P E
AU  - Leaes PE
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Cardiac Surgical Procedures
MH  - Cardiomyopathy, Dilated/diagnostic imaging/mortality/physiopathology/*surgery
MH  - Female
MH  - Heart Transplantation
MH  - Heart Ventricles/*surgery
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Quality of Life
MH  - Survival Analysis
MH  - Ultrasonography
MH  - Vascular Resistance
EDAT- 2001/06/21 10:00
MHDA- 2001/10/26 10:01
CRDT- 2001/06/21 10:00
PHST- 2001/06/21 10:00 [pubmed]
PHST- 2001/10/26 10:01 [medline]
PHST- 2001/06/21 10:00 [entrez]
AID - 10.1111/j.1540-8191.2000.tb00454.x [doi]
PST - ppublish
SO  - J Card Surg. 2000 May-Jun;15(3):179-85. doi: 10.1111/j.1540-8191.2000.tb00454.x.