PMID- 11421432
OWN - NLM
STAT- MEDLINE
DCOM- 20010628
LR  - 20131121
IS  - 0028-8446 (Print)
IS  - 0028-8446 (Linking)
VI  - 114
IP  - 1131
DP  - 2001 May 11
TI  - Adverse events regional feasibility study: methodological results.
PG  - 200-2
AB  - AIMS: To assess the feasibility of research into the occurrence, causation and 
      prevention of adverse events (AEs) in New Zealand public hospitals. METHODS: A 
      two-stage retrospective review was carried out on 1,575 medical records selected 
      by systematic list sample from admissions for 1995 in three public hospitals in 
      the Auckland region. Following initial screening, medical records were subject to 
      structured implicit review using a standardised protocol. Feasibility measures, 
      using international benchmarks where possible, were: adequacy of sample 
      selection; completeness of medical records; reliability and validity of screener 
      and reviewer judgements; internal consistency and face validity of AE 
      determination and preventability assessment. RESULTS: The sample selection 
      procedure was effective, although nearly 10% of records could not be secured. 
      Information in medical records was sufficient for the identification and analysis 
      of AEs. Adequate levels of agreement were achieved for screener and reviewer 
      judgements, with kappa scores ranging between 0.302 and 0.622 and positive 
      predictive values between 50.0% and 89.7%. The criteria for AE determination 
      showed internal consistency and face validity, as did those for preventability. 
      CONCLUSIONS: Research into the occurrence, causation and prevention of AEs in New 
      Zealand health care settings is methodologically feasible and meets international 
      benchmark standards.
FAU - Davis, P
AU  - Davis P
AD  - Department of Public Health and General Practice, Christchurch School of 
      Medicine, University of Otago, New Zealand. Peter.Davis@chmeds.ac.nz
FAU - Lay-Yee, R
AU  - Lay-Yee R
FAU - Schug, S
AU  - Schug S
FAU - Briant, R
AU  - Briant R
FAU - Scott, A
AU  - Scott A
FAU - Johnson, S
AU  - Johnson S
FAU - Bingley, W
AU  - Bingley W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - New Zealand
TA  - N Z Med J
JT  - The New Zealand medical journal
JID - 0401067
SB  - IM
CIN - N Z Med J. 2001 Aug 24;114(1138):387. PMID: 11589444
MH  - Algorithms
MH  - Benchmarking/*methods
MH  - *Drug Therapy
MH  - *Drug-Related Side Effects and Adverse Reactions
MH  - Feasibility Studies
MH  - *Hospitals, Public
MH  - Humans
MH  - *Medical Records
MH  - New Zealand
MH  - Reproducibility of Results
EDAT- 2001/06/26 10:00
MHDA- 2001/06/29 10:01
CRDT- 2001/06/26 10:00
PHST- 2001/06/26 10:00 [pubmed]
PHST- 2001/06/29 10:01 [medline]
PHST- 2001/06/26 10:00 [entrez]
PST - ppublish
SO  - N Z Med J. 2001 May 11;114(1131):200-2.