PMID- 11424510
OWN - NLM
STAT- MEDLINE
DCOM- 20011228
LR  - 20211203
IS  - 0952-3871 (Print)
IS  - 0952-3871 (Linking)
VI  - 14
IP  - 3
DP  - 2001 Jun
TI  - The effect of weekly iron supplementation on anaemia and on iron deficiency among 
      female tea pluckers in Bangladesh.
PG  - 185-90
AB  - AIM: To investigate the effect of weekly iron supplementation on anaemia and iron 
      deficiency among adult, female tea pluckers. METHOD: A randomized double-blind 
      intervention trial was conducted in a tea estate in Bangladesh where a total of 
      280 women received either weekly iron supplementation (200 mg ferrous fumarate 
      and 200 mg folic acid) for 24 weeks or a matching placebo. Capillary blood 
      samples were drawn at baseline and post-trial to determine haemoglobin, 
      haematocrit and ferritin concentration. Mean corpuscular haemoglobin 
      concentration (MCHC) was calculated using the haemoglobin and haematocrit values. 
      RESULTS: The mean haemoglobin concentration in the supplemented group increased 
      by 5.52 g L-1 over the study period, on average, while ferritin values decreased 
      by 0.33 microgram L-1. The control group showed a decrease in both mean 
      haemoglobin (-0.24 g L-1) and ferritin (-5.32 micrograms L-1). Those individuals 
      in the supplemented group with the lowest pretrial haemoglobin and ferritin 
      values experienced the greatest improvements post-trial, whereas nonanaemic 
      individuals showed a decrease in both haemoglobin and ferritin concentrations. A 
      total of 62.2% of women in the supplemented group reported feeling better and 
      more energetic compared to 51.1% in the placebo group; 14.4% of the supplemented 
      group and 22.7% of the control group complained about side-effects. CONCLUSION: 
      Weekly iron supplementation was logistically simpler and cheaper than daily 
      supplementation but would have to be continued on a longer term basis in order to 
      combat both anaemia and iron deficiency.
FAU - Gilgen, D
AU  - Gilgen D
AD  - Department of Biological Anthropology, University of Cambridge, Downing Street, 
      Cambridge CB2 3DZ, UK.
FAU - Mascie-Taylor, C G
AU  - Mascie-Taylor CG
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Hum Nutr Diet
JT  - Journal of human nutrition and dietetics : the official journal of the British 
      Dietetic Association
JID - 8904840
RN  - 0 (Hemoglobins)
RN  - 0 (Tea)
RN  - 9007-73-2 (Ferritins)
RN  - E1UOL152H7 (Iron)
SB  - IM
MH  - Adult
MH  - Agriculture
MH  - Anemia, Iron-Deficiency/blood/*drug therapy/prevention & control
MH  - Bangladesh
MH  - *Dietary Supplements
MH  - Double-Blind Method
MH  - Drug Administration Schedule
MH  - Erythrocytes/chemistry
MH  - Female
MH  - Ferritins/*blood
MH  - Hematocrit
MH  - Hemoglobins/*drug effects
MH  - Humans
MH  - Iron/*administration & dosage/adverse effects
MH  - Iron Deficiencies
MH  - Tea
EDAT- 2001/06/27 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/06/27 10:00
PHST- 2001/06/27 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/06/27 10:00 [entrez]
AID - 10.1046/j.1365-277x.2001.00291.x [doi]
PST - ppublish
SO  - J Hum Nutr Diet. 2001 Jun;14(3):185-90. doi: 10.1046/j.1365-277x.2001.00291.x.