PMID- 11429627
OWN - NLM
STAT- MEDLINE
DCOM- 20010809
LR  - 20191025
IS  - 0958-0670 (Print)
IS  - 0958-0670 (Linking)
VI  - 86
IP  - 1
DP  - 2001 Jan
TI  - Effect of caffeine co-ingested with carbohydrate or fat on metabolism and 
      performance in endurance-trained men.
PG  - 137-44
AB  - We examined the effect of caffeine co-ingested with either carbohydrate or fat on 
      metabolism and performance in eight endurance-trained subjects who performed a 
      random order of four experimental trials consisting of 120 min of steady-state 
      ergometer cycling at 70 % of maximal O(2) uptake (SS) followed by a time trial in 
      which subjects completed a set amount of work (7 kJ kg-1) as quickly as possible. 
      One hour before SS subjects ingested either 2.6 g kg-1 carbohydrate (CHO); 2.6 g 
      kg-1 CHO + 6 mg kg-1 caffeine (CHO + CAF); 1.2 g kg-1 fat with 2000 U I.V. 
      heparin (FAT); or 1.2 g kg-1 fat with 2000 U I.V. heparin + 6 mg kg-1 caffeine 
      (FAT + CAF). The rate of carbohydrate oxidation was higher (micromol kg-1 min-1: 
      CHO, 243 +/- 39 and CHO + CAF, 239 +/- 30 vs. FAT, 196 +/- 48 and FAT + CAF, 191 
      +/- 55; P < 0.05, values are means +/- S.D.) and the rate of fat oxidation lower 
      (micromol kg-1 min-1: CHO, 19 +/- 8 and CHO + CAF, 22 +/- 7 vs. FAT, 35 +/- 19 
      and FAT + CAF, 37 +/- 17; P < 0.05) with carbohydrate than fat ingestion. Yet 
      despite lower carbohydrate use with fat feeding, the time taken to complete the 
      time trial was less after carbohydrate than after fat ingestion (min: CHO, 30.37 
      +/- 7.42 and CHO + CAF, 29.12 +/- 5.62 vs. FAT, 33.02 +/- 8.50 and FAT + CAF, 
      32.78 +/- 7.70; P < 0.05). We conclude that (1) caffeine co-ingested with either 
      carbohydrate or fat meals has no additive effect on substrate utilization or 
      exercise performance and (2) carbohydrate ingestion before exercise improves 
      subsequent time trial performance compared with fat ingestion. Experimental 
      Physiology (2001) 86.1, 137-144.
FAU - Jacobson, T L
AU  - Jacobson TL
AD  - Exercise Metabolism Group, Department of Human Biology and Movement Science, RMIT 
      University, Bundoora 3083, Victoria, Australia.
FAU - Febbraio, M A
AU  - Febbraio MA
FAU - Arkinstall, M J
AU  - Arkinstall MJ
FAU - Hawley, J A
AU  - Hawley JA
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - England
TA  - Exp Physiol
JT  - Experimental physiology
JID - 9002940
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 3G6A5W338E (Caffeine)
SB  - IM
MH  - Adult
MH  - Blood/metabolism
MH  - Caffeine/*pharmacology
MH  - Dietary Carbohydrates/*pharmacology
MH  - Dietary Fats/*pharmacology
MH  - Energy Metabolism/drug effects
MH  - Heart Rate/drug effects
MH  - Homeostasis/drug effects
MH  - Humans
MH  - Male
MH  - Metabolism/*drug effects
MH  - Oxidation-Reduction
MH  - *Physical Education and Training
MH  - *Physical Endurance
MH  - Physical Exertion/drug effects
MH  - Time Factors
EDAT- 2001/06/29 10:00
MHDA- 2001/08/10 10:01
CRDT- 2001/06/29 10:00
PHST- 2001/06/29 10:00 [pubmed]
PHST- 2001/08/10 10:01 [medline]
PHST- 2001/06/29 10:00 [entrez]
AID - EPH_2072 [pii]
AID - 10.1113/eph8602072 [doi]
PST - ppublish
SO  - Exp Physiol. 2001 Jan;86(1):137-44. doi: 10.1113/eph8602072.