PMID- 11442890
OWN - NLM
STAT- MEDLINE
DCOM- 20011004
LR  - 20061115
IS  - 1323-1316 (Print)
IS  - 1323-1316 (Linking)
VI  - 55
IP  - 4
DP  - 2001 Aug
TI  - Correlation of panic attacks and hostility in chronic schizophrenia.
PG  - 383-7
AB  - The aim of this study was to investigate the relationship between panic attacks 
      and hostility in patients with chronic schizophrenia. Thirty-two patients with a 
      minimum 2-year history of treatment for schizophrenia were interviewed. The 
      patients took mood stablizers lithium, carbamazepine and valproate adjunctively 
      for hostility and anger attacks. Panic attacks were defined by Structure Clinical 
      Interview of DSM-IV. Severity of psychopathology was assessed by the Hamilton 
      Depression Rating Scale (HDRS) and Brief Psychiatric Rating Scale (BPRS). 
      Functional level was assessed by the Global Assessment of Functioning Scale 
      (GAF). Eight (25%) patients met the diagnostic criteria for panic attacks 
      (DSM-IV) with affective symptoms including hostility and sudden spells of anger. 
      Their HDRS scores were significantly higher (P < 0.01), and GAF scores were 
      significantly lower (P < 0.05) than those of patients without panic attacks. 
      Patients with panic attacks displayed significantly higher hostility in the score 
      of the BPRS (P = 0.01). Those who received higher doses of neuroleptics were more 
      likely to be considered hostile. Multivariate analysis revealed that panic 
      attacks were correlated with more severe depression, greater hostility and lower 
      GAF scores. The results suggest that increased hostility and anger spells may be 
      symptoms of panic attacks, which are overlooked by psychiatrists.
FAU - Chen, C Y
AU  - Chen CY
AD  - Department of Psychiatry, Chang-Gung Memorial Hospital and Chang-Gung University 
      School of Medicine, 5 Fu-Shing, St, Kweishan, Taoyuan 333, Taiwan.
FAU - Liu, C Y
AU  - Liu CY
FAU - Yang, Y Y
AU  - Yang YY
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Australia
TA  - Psychiatry Clin Neurosci
JT  - Psychiatry and clinical neurosciences
JID - 9513551
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Adult
MH  - Antipsychotic Agents/therapeutic use
MH  - Chronic Disease
MH  - Depression/psychology
MH  - Female
MH  - *Hostility
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Panic Disorder/*complications/drug therapy/psychology
MH  - Schizophrenia/*complications
MH  - *Schizophrenic Psychology
MH  - Severity of Illness Index
EDAT- 2001/07/10 10:00
MHDA- 2001/10/05 10:01
CRDT- 2001/07/10 10:00
PHST- 2001/07/10 10:00 [pubmed]
PHST- 2001/10/05 10:01 [medline]
PHST- 2001/07/10 10:00 [entrez]
AID - pcn879 [pii]
AID - 10.1046/j.1440-1819.2001.00879.x [doi]
PST - ppublish
SO  - Psychiatry Clin Neurosci. 2001 Aug;55(4):383-7. doi: 
      10.1046/j.1440-1819.2001.00879.x.