PMID- 11455537
OWN - NLM
STAT- MEDLINE
DCOM- 20010906
LR  - 20190117
IS  - 0003-276X (Print)
IS  - 0003-276X (Linking)
VI  - 263
IP  - 3
DP  - 2001 Jul 1
TI  - The ferret's vomeronasal organ and accessory olfactory bulb: effect of hormone 
      manipulation in adult males and females.
PG  - 280-8
AB  - The male ferret, a carnivore, was recently shown to possess a vomeronasal organ 
      (VNO). We compared the morphology of the VNO and its associated accessory 
      olfactory bulb (AOB) in male and female ferrets that were killed in adulthood. 
      The volume and surface area of the VNO neuroepithelium were similar in adult 
      gonadectomized male and female ferrets regardless of whether they were treated 
      with testosterone propionate (TP) or oil vehicle. An AOB was localized 
      bilaterally in the medial caudal part of the olfactory bulbs of adult ferrets 
      using soybean agglutin binding and immunostaining for luteinizing 
      hormone-releasing hormone and tyrosine hydroxylase as well as Nissl staining of 
      coronal, horizontal, and sagittal brain sections. There was no effect of sex or 
      TP treatment on AOB cell layer volume in adult gonadectomized animals. We found 
      the ferret's AOB to be more medially located and much smaller than previously 
      reported in this species, thus highlighting the importance of using several 
      histochemical markers to characterize this structure in any previously unexamined 
      species. Adult male and female ferrets both have a VNO and an associated AOB. 
      More research is needed to determine what role, if any, this accessory olfactory 
      system plays in mediating behavioral and neuroendocrine responses to pheromones 
      in ferrets of either sex.
CI  - Copyright 2001 Wiley-Liss, Inc.
FAU - Kelliher, K R
AU  - Kelliher KR
AD  - Department of Biology, Boston University, Boston, MA 02215, USA. 
      kkell002@umaryland.edu
FAU - Baum, M J
AU  - Baum MJ
FAU - Meredith, M
AU  - Meredith M
LA  - eng
GR  - DC 00906/DC/NIDCD NIH HHS/United States
GR  - HD 21094/HD/NICHD NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Anat Rec
JT  - The Anatomical record
JID - 0370540
RN  - 0 (Gonadal Steroid Hormones)
RN  - 0 (Lectins)
RN  - 0 (Plant Lectins)
RN  - 0 (Soybean Proteins)
RN  - 0 (soybean lectin)
RN  - 33515-09-2 (Gonadotropin-Releasing Hormone)
RN  - 3XMK78S47O (Testosterone)
RN  - EC 1.14.16.2 (Tyrosine 3-Monooxygenase)
SB  - IM
MH  - Animals
MH  - Female
MH  - Ferrets/*anatomy & histology
MH  - Gonadal Steroid Hormones/*pharmacology
MH  - Gonadotropin-Releasing Hormone/analysis
MH  - Histocytochemistry
MH  - Lectins/analysis
MH  - Male
MH  - Nissl Bodies
MH  - Olfactory Bulb/*anatomy & histology/chemistry/drug effects
MH  - *Plant Lectins
MH  - Sex Characteristics
MH  - *Soybean Proteins
MH  - Testosterone/*pharmacology
MH  - Tyrosine 3-Monooxygenase/analysis
MH  - Vomeronasal Organ/*anatomy & histology/chemistry/drug effects
EDAT- 2001/07/17 10:00
MHDA- 2001/09/08 10:01
CRDT- 2001/07/17 10:00
PHST- 2001/07/17 10:00 [pubmed]
PHST- 2001/09/08 10:01 [medline]
PHST- 2001/07/17 10:00 [entrez]
AID - 10.1002/ar.1097 [pii]
AID - 10.1002/ar.1097 [doi]
PST - ppublish
SO  - Anat Rec. 2001 Jul 1;263(3):280-8. doi: 10.1002/ar.1097.