PMID- 11457801
OWN - NLM
STAT- MEDLINE
DCOM- 20010927
LR  - 20181130
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 91
IP  - 2
DP  - 2001 Aug
TI  - Addition of protein and amino acids to carbohydrates does not enhance 
      postexercise muscle glycogen synthesis.
PG  - 839-46
AB  - Ingestion of a protein-amino acid mixture (Pro; wheat protein hydrolysate, 
      leucine, and phenylalanine) in combination with carbohydrate (CHO; 0.8 g x kg(-1) 
      x h(-1)) has been shown to increase muscle glycogen synthesis after exercise 
      compared with the same amount of CHO without Pro. The aim of this study was to 
      investigate whether coingestion of Pro also increases muscle glycogen synthesis 
      when 1.2 g CHO. kg(-1). h(-1) is ingested. Eight male cyclists performed two 
      experimental trials separated by 1 wk. After glycogen-depleting exercise, 
      subjects received either CHO (1.2 g x kg(-1) x h(-1)) or CHO+Pro (1.2 g CHO x 
      kg(-1) x h(-1) + 0.4 g Pro x kg(-1) x h(-1)) during a 3-h recovery period. Muscle 
      biopsies were obtained immediately, 1 h, and 3 h after exercise. Blood samples 
      were collected immediately after the exercise bout and every 30 min thereafter. 
      Plasma insulin was significantly higher in the CHO+Pro trial compared with the 
      CHO trial (P < 0.05). No difference was found in plasma glucose or in rate of 
      muscle glycogen synthesis between the CHO and the CHO+Pro trials. Although 
      coingestion of a protein amino acid mixture in combination with a large CHO 
      intake (1.2 g x kg(-1) x h(-1)) increases insulin levels, this does not result in 
      increased muscle glycogen synthesis.
FAU - Jentjens, R L
AU  - Jentjens RL
AD  - Human Performance Laboratory, School of Sport and Exercise Sciences, University 
      of Birmingham, Birmingham B15 2TT, United Kingdom.
FAU - van Loon, L J
AU  - van Loon LJ
FAU - Mann, C H
AU  - Mann CH
FAU - Wagenmakers, A J
AU  - Wagenmakers AJ
FAU - Jeukendrup, A E
AU  - Jeukendrup AE
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Amino Acids)
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Insulin)
RN  - 0 (Plant Proteins, Dietary)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Adult
MH  - Amino Acids/metabolism/*pharmacology
MH  - Bicycling
MH  - Blood Glucose/metabolism
MH  - Dietary Carbohydrates/*metabolism
MH  - Dietary Proteins/metabolism/*pharmacology
MH  - Exercise/*physiology
MH  - Glycogen/biosynthesis/*metabolism
MH  - Humans
MH  - Insulin/blood
MH  - Male
MH  - Muscle, Skeletal/*metabolism
MH  - Physical Endurance
MH  - Physical Exertion/*physiology
MH  - Plant Proteins, Dietary
MH  - Time Factors
MH  - Triticum
EDAT- 2001/07/18 10:00
MHDA- 2001/09/28 10:01
CRDT- 2001/07/18 10:00
PHST- 2001/07/18 10:00 [pubmed]
PHST- 2001/09/28 10:01 [medline]
PHST- 2001/07/18 10:00 [entrez]
AID - 10.1152/jappl.2001.91.2.839 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 2001 Aug;91(2):839-46. doi: 10.1152/jappl.2001.91.2.839.