PMID- 11463459
OWN - NLM
STAT- MEDLINE
DCOM- 20010809
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 128
IP  - 2
DP  - 2001 Jul 15
TI  - Trisomy 16 as the sole anomaly in hematological malignancies. Three new cases and 
      a short review.
PG  - 168-71
AB  - We report on three cases, two with myelodysplastic syndrome (MDS) and one with 
      acute lymphoblastic leukemia (ALL), displaying trisomy 16 as the sole cytogenetic 
      anomaly. In none of these cases was a concomitant inv(16)(p13q22) detected by 
      fluorescence in situ hybridization (FISH) or reverse transcription polymerase 
      chain reaction (RT-PCR). Summarizing the literature, only six other cases 
      cytogenetically characterized by an isolated trisomy 16 have been reported in 
      hematological malignancies. These patients had either MDS, acute myeloblastic 
      leukemia (AML), myelofibrosis, or ALL. All but one of these cases were aged less 
      than 50.
FAU - Guillaume, B
AU  - Guillaume B
AD  - Department of Hematology, Cliniques Universitaires St Luc, Universite Catholique 
      de Louvain, Brussels, Belgium.
FAU - Ameye, G
AU  - Ameye G
FAU - Dierlamm, J
AU  - Dierlamm J
FAU - Verhoef, G
AU  - Verhoef G
FAU - Duhem, C
AU  - Duhem C
FAU - Ferrant, A
AU  - Ferrant A
FAU - Hagemeijer, A
AU  - Hagemeijer A
FAU - Verellen-Dumoulin, C
AU  - Verellen-Dumoulin C
FAU - Michaux, L
AU  - Michaux L
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Adult
MH  - *Chromosomes, Human, Pair 16
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myelodysplastic Syndromes/*genetics
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - *Trisomy
RF  - 8
EDAT- 2001/07/21 10:00
MHDA- 2001/08/10 10:01
CRDT- 2001/07/21 10:00
PHST- 2001/07/21 10:00 [pubmed]
PHST- 2001/08/10 10:01 [medline]
PHST- 2001/07/21 10:00 [entrez]
AID - S0165-4608(01)00401-0 [pii]
AID - 10.1016/s0165-4608(01)00401-0 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 2001 Jul 15;128(2):168-71. doi: 
      10.1016/s0165-4608(01)00401-0.