PMID- 1147340
OWN - NLM
STAT- MEDLINE
DCOM- 19751003
LR  - 20031114
IS  - 0002-9645 (Print)
IS  - 0002-9645 (Linking)
VI  - 36
IP  - 7
DP  - 1975 Jul
TI  - Tarsal degenerative joint disease in cattle: blood and synovial fluid changes.
PG  - 1009-14
AB  - Tarsal degenerative joint disease (DJD) in 27 cattle was classified as primary or 
      secondary based on age, joint conformation defects, faulty hindlimb alignment, or 
      history of trauma to the affected joint(s). Results of blood and synovial fluid 
      analysis for cattle affected with primary or secondary tarsal DJD were grouped in 
      compilation of data. Cattle with tarsal DJD had significantly (P smaller than 
      0.01) reduced hemoglobin (Hb) content in comparison to that in control cattle. 
      There was highly significant (P smaller than 0.001) reduction in packed cell 
      volume (PCV). A significant difference was not determined for mean corpuscular 
      hemoglobin concentration (MCHC) values of the 2 groups of cattle. Total white 
      blood cell (WBC) counts closely paralleled each other, although mean proportion 
      of neutrophils was significantly (P smaller than 0.05) greater in cattle affected 
      with tarsal DJD, as were mean proportion of lymphocytes (P smaller than 0.02). 
      Synovial fluid samples were analyzed for physical, biochemical, and cytologic 
      properties. Statistical comparisons were made between values determined for 
      arthritic cattle and control cattle. All samples from cattle with tarsal DJD were 
      transudative. Opacity and flocculation were attributed to the presence of 
      cartilaginous fragments and fibrils. There was significant correlation between 
      increased relative viscosity (RV) and higher grades of mucinous precipitate 
      quality (MPQ; r = +0.294, P smaller than 0.05) for all cattle. Mean alkaline 
      phosphatase (ALP) activity for arthritic cattle was significantly (P smaller than 
      0.001) reduced, as was the mean activity for lactic dehydrogenase (LDH; P smaller 
      than 0.05). The mean aldolase (ALD) activity for arthritic cattle was increased, 
      whereas mean activity values for glutamic oxalacetic transaminase (GOT) and 
      glutamic pyruvic transaminase (GPT) were reduced. Samples from arthritic cattle 
      had reduced total leukocyte counts and significantly (P smaller than 0.05) 
      increased proportion of macrophages in comparison to the values in control 
      cattle.
FAU - Van Pelt, R W
AU  - Van Pelt RW
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Vet Res
JT  - American journal of veterinary research
JID - 0375011
RN  - 0 (Blood Glucose)
RN  - 0 (Carbohydrates)
RN  - 0 (Hemoglobins)
RN  - 0 (Mucins)
RN  - 0 (Proteins)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.6.1.1 (Aspartate Aminotransferases)
RN  - EC 2.6.1.2 (Alanine Transaminase)
RN  - EC 3.1.3.1 (Alkaline Phosphatase)
RN  - EC 4.1.2.13 (Fructose-Bisphosphate Aldolase)
SB  - IM
MH  - Alanine Transaminase/metabolism
MH  - Alkaline Phosphatase/metabolism
MH  - Animals
MH  - Aspartate Aminotransferases/metabolism
MH  - Blood Glucose/analysis
MH  - Carbohydrates/analysis
MH  - Cattle
MH  - *Cattle Diseases/blood
MH  - Female
MH  - Fructose-Bisphosphate Aldolase/metabolism
MH  - Hematocrit
MH  - Hemoglobins/analysis
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Leukocyte Count
MH  - Male
MH  - Mucins/analysis
MH  - Osteoarthritis/blood/*veterinary
MH  - Proteins/analysis
MH  - *Synovial Fluid/analysis/cytology
MH  - *Tarsal Joints
MH  - Viscosity
EDAT- 1975/07/01 00:00
MHDA- 1975/07/01 00:01
CRDT- 1975/07/01 00:00
PHST- 1975/07/01 00:00 [pubmed]
PHST- 1975/07/01 00:01 [medline]
PHST- 1975/07/01 00:00 [entrez]
PST - ppublish
SO  - Am J Vet Res. 1975 Jul;36(7):1009-14.