PMID- 1147375 OWN - NLM STAT- MEDLINE DCOM- 19751011 LR - 20131121 IS - 0003-0805 (Print) IS - 0003-0805 (Linking) VI - 112 IP - 1 DP - 1975 Jul TI - Stability of amphotericin B in polyvinvl chloride intravenous infusion bags. PG - 145-6 AB - The stability of solutions of amphotericin B as prepared for intravenous use in glass and polyvinyl chloride plastic (PVC) containers was studied. Four conditions were tested: contained within glass and exposed to light; contained in glass and shielded from light; contained in PVC and exposed to light; contained in PVC and shielded from light. Bioassays were performed on specimens collected from the containers periodically during 24 hours. Results of the bioassays revealed no significant loss of activity under any of the test conditions. FAU - Tipple, M AU - Tipple M FAU - Shadomy, S AU - Shadomy S FAU - Espinel-Ingroff, A AU - Espinel-Ingroff A LA - eng PT - Journal Article PL - United States TA - Am Rev Respir Dis JT - The American review of respiratory disease JID - 0370523 RN - 0 (Polyvinyls) RN - 7XU7A7DROE (Amphotericin B) RN - 9002-86-2 (Polyvinyl Chloride) SB - IM MH - *Amphotericin B MH - Drug Packaging MH - *Drug Stability MH - Glass MH - Infusions, Parenteral/*instrumentation MH - Light MH - *Polyvinyl Chloride MH - *Polyvinyls EDAT- 1975/07/01 00:00 MHDA- 1975/07/01 00:01 CRDT- 1975/07/01 00:00 PHST- 1975/07/01 00:00 [pubmed] PHST- 1975/07/01 00:01 [medline] PHST- 1975/07/01 00:00 [entrez] AID - 10.1164/arrd.1975.112.1.145 [doi] PST - ppublish SO - Am Rev Respir Dis. 1975 Jul;112(1):145-6. doi: 10.1164/arrd.1975.112.1.145.