PMID- 11484305
OWN - NLM
STAT- MEDLINE
DCOM- 20010927
LR  - 20051116
IS  - 1088-0224 (Print)
IS  - 1088-0224 (Linking)
VI  - 6
IP  - 20 Suppl
DP  - 2000 Nov
TI  - Economics of low-molecular weight heparins.
PG  - S1054-65; quiz 1066-7
AB  - Low-molecular weight heparins (LMWHs) have become attractive alternatives to 
      standard unfractionated heparin (UFH) for the treatment and prophylaxis of deep 
      vein thrombosis (DVT), and for the management of acute coronary syndrome (ACS). 
      The economic impact of the use of LMWHs has been studied in randomized controlled 
      studies, in demonstration projects in managed care institutions, and in decision 
      models. These studies provide valuable insight into the ways LMWHs can be 
      economically attractive despite higher per unit costs compared with UFH. For the 
      treatment of DVT, the cost benefit of using LMWHs results primarily from the cost 
      shifting from inpatient to outpatient care, and might be limited by the 
      eligibility of patients for outpatient management. In contrast, the 
      attractiveness of LMWHs for ACS and DVT prophylaxis hinges on the increased 
      effectiveness of LMWHs compared with standard UFH.
FAU - Rutschmann, O T
AU  - Rutschmann OT
AD  - Duke Center for Clinical Health Policy Research, Duke University Medical Center, 
      Durham, North Carolina, USA.
FAU - Matchar, D B
AU  - Matchar DB
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Am J Manag Care
JT  - The American journal of managed care
JID - 9613960
RN  - 0 (Antifibrinolytic Agents)
RN  - 0 (Heparin, Low-Molecular-Weight)
MH  - Antifibrinolytic Agents/*economics/therapeutic use
MH  - Cost of Illness
MH  - Decision Support Techniques
MH  - Drug Costs
MH  - Education, Medical, Continuing
MH  - Education, Pharmacy, Continuing
MH  - Heparin, Low-Molecular-Weight/*economics/therapeutic use
MH  - Hospital Costs
MH  - Humans
MH  - Managed Care Programs/*economics
MH  - United States
MH  - Venous Thrombosis/drug therapy/*economics
RF  - 51
EDAT- 2001/08/04 10:00
MHDA- 2001/09/28 10:01
CRDT- 2001/08/04 10:00
PHST- 2001/08/04 10:00 [pubmed]
PHST- 2001/09/28 10:01 [medline]
PHST- 2001/08/04 10:00 [entrez]
AID - 755 [pii]
PST - ppublish
SO  - Am J Manag Care. 2000 Nov;6(20 Suppl):S1054-65; quiz 1066-7.