PMID- 11490925
OWN - NLM
STAT- MEDLINE
DCOM- 20020715
LR  - 20191025
IS  - 0930-1038 (Print)
IS  - 0930-1038 (Linking)
VI  - 23
IP  - 3
DP  - 2001 Jun
TI  - Mediastinal lymphatic efferents from the diaphragm.
PG  - 159-62
AB  - The prognosis of non small cell lung cancer (NSCLC) invading the diaphragm is 
      poor, probably due to the richness of the lymphatic drainage of the diaphragm. 
      The aim of this study was to determine mediastinal lymphatic efferents from the 
      diaphragm. The diaphragms of 20 adult cadavers (77-104 years) were injected with 
      a dye (modified Gerota's medium) to permit the lymph vessels to be catheterised 
      and then dissected. Each stage of the dissection was described and photographed: 
      23 injections on the right and 25 on the left. Diaphragmatic lymph vessels passed 
      to one of three lymph centres: posterior (paraaortic nodes, n = 16), anterior 
      (juxtasternal nodes, n = 16) and mediastinal (visceral nodes, n = 16). From these 
      lymph centres arose ascending lymph pathways: posteriorly to the thoracic duct 
      (8/16), anteriorly along the internal thoracic vessels (10/16) and in the 
      mediastinum to the peritracheobronchial nodes (6/10). Lymphatics from the 
      diaphragm are abundant and drain towards mediastinal node lymph centres 
      connecting to the blood stream via the thoracic duct. These lymph pathways are 
      common with those of the pulmonary segments. Poor prognosis of NSCLC invading the 
      diaphragm may be explained by the common lymphatic drainage of both the lung and 
      diaphragm.
FAU - Souilamas, R
AU  - Souilamas R
AD  - Service de Chirurgie Thoracique, Hopital Europeen Georges Pompidou, 20 rue 
      Leblanc, F-75015 Paris, France.
FAU - Hidden, G
AU  - Hidden G
FAU - Riquet, M
AU  - Riquet M
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Surg Radiol Anat
JT  - Surgical and radiologic anatomy : SRA
JID - 8608029
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Cadaver
MH  - Diaphragm/*anatomy & histology
MH  - Female
MH  - Humans
MH  - Lymphatic System/*anatomy & histology
MH  - Male
MH  - Mediastinum/*anatomy & histology
EDAT- 2001/08/09 10:00
MHDA- 2002/07/16 10:01
CRDT- 2001/08/09 10:00
PHST- 2001/08/09 10:00 [pubmed]
PHST- 2002/07/16 10:01 [medline]
PHST- 2001/08/09 10:00 [entrez]
AID - 10.1007/s00276-001-0159-y [doi]
PST - ppublish
SO  - Surg Radiol Anat. 2001 Jun;23(3):159-62. doi: 10.1007/s00276-001-0159-y.