PMID- 11502354
OWN - NLM
STAT- MEDLINE
DCOM- 20011011
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 309
IP  - 2
DP  - 2001 Aug 24
TI  - The spindle neurons are present in the cingulate cortex of chimpanzee fetus.
PG  - 97-100
AB  - We report the existence of the spindle neurons in layer Vb of the anterior 
      cingulate cortex (Brodman's area 24b) in a chimpanzee fetus (embryonic day 224), 
      which was stillborn. About 5.3% of neuronal cells in layer Vb were the spindle 
      neurons at this stage. The width of the spindle neurons was 10-15 microm. In 
      layer V of the prefrontal cortex (Brodman's area 46) in the chimpanzee fetus, and 
      in layer Vb of the cingulate cortex in adult macaque monkeys, no spindle neurons 
      were observed. The immunoreactivity against brain-derived neurotrophic factor 
      (BDNF) was detected only in the pyramidal neurons at this stage. These findings 
      suggest that the existence of the spindle neurons in layer Vb of the anterior 
      cingulate cortex and the presence of BDNF in the pyramidal neurons are 
      intrinsically characterized during the embryonic stage of the chimpanzee.
FAU - Hayashi, M
AU  - Hayashi M
AD  - Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto 
      University, Kanrin, Inuyama, Aichi 484-8506, Japan. hayashi@pri.kyoto-u.ac.jp
FAU - Ito, M
AU  - Ito M
FAU - Shimizu, K
AU  - Shimizu K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/analysis
MH  - Fetus/cytology
MH  - Gyrus Cinguli/*cytology/*embryology
MH  - Male
MH  - Neurons/chemistry/*cytology
MH  - Pan troglodytes
EDAT- 2001/08/15 10:00
MHDA- 2001/10/12 10:01
CRDT- 2001/08/15 10:00
PHST- 2001/08/15 10:00 [pubmed]
PHST- 2001/10/12 10:01 [medline]
PHST- 2001/08/15 10:00 [entrez]
AID - S0304-3940(01)02039-0 [pii]
AID - 10.1016/s0304-3940(01)02039-0 [doi]
PST - ppublish
SO  - Neurosci Lett. 2001 Aug 24;309(2):97-100. doi: 10.1016/s0304-3940(01)02039-0.