PMID- 11504292
OWN - NLM
STAT- MEDLINE
DCOM- 20011207
LR  - 20191025
IS  - 1445-1433 (Print)
IS  - 1445-1433 (Linking)
VI  - 71
IP  - 8
DP  - 2001 Aug
TI  - Endocrine tumours of the pancreas: review and recent advances.
PG  - 475-82
AB  - Pancreatic endocrine tumours (PET) are rare but nonetheless important to 
      recognize and treat in a timely fashion. Significant morbidity occurs due to 
      excess secretion of hormones, with all of the PET having some degree of malignant 
      potential. Surgeons must plan directed operative strategies to deal with these 
      tumours and be prepared to undertake aggressive palliative debulking resections 
      if indicated. Somatostatin receptor scintigraphy and endoscopic ultrasound have 
      been particularly helpful in both localizing and staging patients with PET. Other 
      important advances in management include the use of long-acting somatostatin 
      analogues to inhibit hormonal secretion and tumour growth. The possibility of 
      multiple endocrine neoplasia type 1 (MEN-1) should be considered in any patient 
      with a PET. The present article will review the various classes of PET, describe 
      MEN-1 in relation to PET and examine advances in imaging and localization. The 
      role of surgery for PET is also discussed in the present review.
FAU - Mullan, M H
AU  - Mullan MH
AD  - Department of Surgery, Division of Endocrine Surgery, University of Michigan 
      Hospital, Ann Arbor 48109-0331, USA.
FAU - Gauger, P G
AU  - Gauger PG
FAU - Thompson, N W
AU  - Thompson NW
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Australia
TA  - ANZ J Surg
JT  - ANZ journal of surgery
JID - 101086634
SB  - IM
MH  - Adenoma, Islet Cell/*pathology/*therapy
MH  - Carcinoma, Islet Cell/*pathology/*therapy
MH  - Humans
MH  - Multiple Endocrine Neoplasia Type 1/*pathology/*therapy
MH  - Pancreatic Neoplasms/*pathology/*therapy
RF  - 40
EDAT- 2001/08/16 10:00
MHDA- 2002/01/05 10:01
CRDT- 2001/08/16 10:00
PHST- 2001/08/16 10:00 [pubmed]
PHST- 2002/01/05 10:01 [medline]
PHST- 2001/08/16 10:00 [entrez]
AID - 10.1046/j.1440-1622.2001.02191.x [doi]
PST - ppublish
SO  - ANZ J Surg. 2001 Aug;71(8):475-82. doi: 10.1046/j.1440-1622.2001.02191.x.