PMID- 11509106
OWN - NLM
STAT- MEDLINE
DCOM- 20010830
LR  - 20151119
IS  - 0007-1145 (Print)
IS  - 0007-1145 (Linking)
VI  - 85 Suppl 2
DP  - 2001 May
TI  - Prospects of fortification of salt with iron and iodine.
PG  - S167-73
AB  - Fortification of salt with iron has been developed by the National Institute of 
      Nutrition (NIN) as a strategy for the control of iron deficiency anaemia (IDA) in 
      India, similar to iodization of salt for control of iodine deficiency disorders 
      (IDD). Stability of the iron fortified salt (IFS), its bioavailability and 
      organoleptic evaluation of food items containing the IFS have been demonstrated. 
      Acceptability and effectiveness of the IFS in school children and in multicentric 
      community trials have been demonstrated. With the introduction of universal 
      iodization of salt as a national policy in 1988, NIN has developed a formulation 
      for double fortification (DFS) of salt with iodine and iron. The stability of the 
      nutrients under laboratory conditions along with their bioavailability were found 
      to be good but varying with the quality of salt used. The DFS has been evaluated 
      in controlled trials in tribal communities and in residential school children. 
      The findings of these studies are discussed. Overall, in these trials, DFS 
      effectively controlled iodine deficiency but a clear impact on reducing anaemia 
      was not demonstrated. In residential schoolchildren, increased urinary excretion 
      of iodine as well as reduced anaemia were observed. The quality of salt has been 
      found to be an important determinant of the stability of iodine in DFS. Further 
      evaluation of this potentially important intervention is in progress.
FAU - Sivakumar, B
AU  - Sivakumar B
AD  - National Institute of Nutrition, Jamai Osmania Post, Hyderabad - 500 007, India. 
      nin@ap.ap.nic.in
FAU - Brahmam, G N
AU  - Brahmam GN
FAU - Madhavan Nair, K
AU  - Madhavan Nair K
FAU - Ranganathan, S
AU  - Ranganathan S
FAU - Vishnuvardhan Rao, M
AU  - Vishnuvardhan Rao M
FAU - Vijayaraghavan, K
AU  - Vijayaraghavan K
FAU - Krishnaswamy, K
AU  - Krishnaswamy K
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Hemoglobins)
RN  - 0 (Micronutrients)
RN  - 27YLU75U4W (Phosphorus)
RN  - 451W47IQ8X (Sodium Chloride)
RN  - 9679TC07X4 (Iodine)
RN  - E1UOL152H7 (Iron)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - Adolescent
MH  - Anemia, Iron-Deficiency/blood/*therapy
MH  - Biological Availability
MH  - Calcium/metabolism
MH  - Child
MH  - Child, Preschool
MH  - Feasibility Studies
MH  - Female
MH  - *Food, Fortified
MH  - Goiter, Endemic/therapy
MH  - Hemoglobins/analysis
MH  - Homeostasis
MH  - Humans
MH  - India
MH  - *Iodine/urine
MH  - *Iron/administration & dosage/pharmacokinetics
MH  - Male
MH  - *Micronutrients/administration & dosage/pharmacokinetics
MH  - Phosphorus/metabolism
MH  - *Sodium Chloride/administration & dosage/pharmacokinetics
EDAT- 2001/08/18 10:00
MHDA- 2001/08/31 10:01
CRDT- 2001/08/18 10:00
PHST- 2001/08/18 10:00 [pubmed]
PHST- 2001/08/31 10:01 [medline]
PHST- 2001/08/18 10:00 [entrez]
AID - S0007114501001076 [pii]
PST - ppublish
SO  - Br J Nutr. 2001 May;85 Suppl 2:S167-73.