PMID- 11510666
OWN - NLM
STAT- MEDLINE
DCOM- 20011101
LR  - 20230307
IS  - 0362-028X (Print)
IS  - 0362-028X (Linking)
VI  - 64
IP  - 8
DP  - 2001 Aug
TI  - High-performance liquid chromatographic determination of carbadox, olaquindox, 
      furazolidone, nitrofurazone, and nitrovin in feed.
PG  - 1231-4
AB  - A high-performance liquid chromatography with gradient programming method was 
      developed to determine the amount of carbadox (CBX), olaquindox (OLQ), 
      furazolidone (FZ), nitrofurazone (NF), and nitrovin (NTV) in feed simultaneously. 
      Complete separation of the drugs was obtained using a C8 silica gel column with 
      gradients of acetonitrile as mobile phase. The mobile phase used an acetonitrile 
      gradient with an initial hold time of 1 min at 0% acetonitrile, followed by an 
      increase to 50% acetonitrile over 10 min. The correlation coefficients (r) for 
      calibration curves of the five feed additives were greater than 0.999. The 
      relative standard deviations (RSDs) of peak areas from four injections for these 
      drugs at three concentrations were less than 3.0%, although the RSD for NTV at 5 
      ppm was somewhat large (6.7%). The medicated feeds were extracted by pretreating 
      with water, extracted with 95% dimethylformamide overnight at room temperature, 
      and cleaned up on a column of alumina oxide. Recoveries of CBX, OLQ, FZ, NF, and 
      NTV from low level spiked feed were 102.0, 94.6, 97.4, 110.6, and 66.0%, 
      respectively, and from high level spiked feed, they were 114.09, 99.1, 97.3, 
      109.9, and 62.7%, respectively.
FAU - Lin, S Y
AU  - Lin SY
AD  - National Institute for Animal Health, Council of Agriculture, Executive Yuan, 
      Taipei, Taiwan, Republic of China. director@mail.tahri.gov.tw
FAU - Jeng, S L
AU  - Jeng SL
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Food Prot
JT  - Journal of food protection
JID - 7703944
RN  - 0 (Anti-Infective Agents)
RN  - 0 (Quinoxalines)
RN  - 4I203628MT (Nitrovin)
RN  - 5J9CPU3RE0 (Furazolidone)
RN  - G3LAW9U88T (olaquindox)
RN  - M2X04R2E2Y (Carbadox)
RN  - X8XI70B5Z6 (Nitrofurazone)
SB  - IM
MH  - Animal Feed/*analysis
MH  - Anti-Infective Agents/*analysis
MH  - Calibration
MH  - Carbadox/analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Furazolidone/analysis
MH  - Nitrofurazone/analysis
MH  - Nitrovin/analysis
MH  - Quinoxalines/analysis
MH  - Sensitivity and Specificity
EDAT- 2001/08/21 10:00
MHDA- 2001/11/03 10:01
CRDT- 2001/08/21 10:00
PHST- 2001/08/21 10:00 [pubmed]
PHST- 2001/11/03 10:01 [medline]
PHST- 2001/08/21 10:00 [entrez]
AID - S0362-028X(22)04633-6 [pii]
AID - 10.4315/0362-028x-64.8.1231 [doi]
PST - ppublish
SO  - J Food Prot. 2001 Aug;64(8):1231-4. doi: 10.4315/0362-028x-64.8.1231.