PMID- 11516746 OWN - NLM STAT- MEDLINE DCOM- 20010906 LR - 20190921 IS - 1388-2457 (Print) IS - 1388-2457 (Linking) VI - 112 IP - 7 DP - 2001 Jul TI - Two evoked responses with different recovery functions in the primary somatosensory cortex in humans. PG - 1334-42 AB - OBJECTIVES: We investigated the recovery function of somatosensory evoked magnetic cortical fields (SEFs) to confirm the temporal aspects of the somatosensory process in humans. METHODS: SEFs were recorded following median nerve electrical stimulation in 6 healthy subjects. Double stimulation, with interstimulus intervals (ISIs) from 3 to 100 ms, was applied, and the SEF components for the second stimulation were analyzed. In a supplementary experiment, responses to single stimulations of various intensities from the sensory threshold to the motor threshold were studied. RESULTS: The first SEF component (1M) diminished when the ISI was less than 10 ms, while the second component (2M) remained even when the ISI was 3 ms. The two components showed a very similar attenuation with decrease of stimulus intensity. There was no significant difference in dipole location between 1M and 2M in the primary somatosensory cortex (SI). CONCLUSIONS: The results suggested that at least two independent pathways with different recovery functions exist in a similar area in the SI. FAU - Hoshiyama, M AU - Hoshiyama M AD - Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8585, Japan. hosiyama@nips.ac.jp FAU - Kakigi, R AU - Kakigi R LA - eng PT - Clinical Trial PT - Journal Article PL - Netherlands TA - Clin Neurophysiol JT - Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology JID - 100883319 SB - IM MH - Adult MH - Brain Mapping MH - Electric Stimulation MH - Evoked Potentials, Somatosensory/*physiology MH - Female MH - Humans MH - Magnetoencephalography MH - Male MH - Median Nerve/physiology MH - Neurons/physiology MH - Somatosensory Cortex/cytology/*physiology EDAT- 2001/08/23 10:00 MHDA- 2001/09/08 10:01 CRDT- 2001/08/23 10:00 PHST- 2001/08/23 10:00 [pubmed] PHST- 2001/09/08 10:01 [medline] PHST- 2001/08/23 10:00 [entrez] AID - S1388-2457(01)00564-8 [pii] AID - 10.1016/s1388-2457(01)00564-8 [doi] PST - ppublish SO - Clin Neurophysiol. 2001 Jul;112(7):1334-42. doi: 10.1016/s1388-2457(01)00564-8.